research Painful thickened skin on the soles of the feet
The man has a genetic skin condition called pachyonychia congenita.
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research Biotinidase deficiency characterized by skin and hair findings
Biotin supplements improved skin and hair problems in a girl with biotinidase deficiency.
research Merkel cell polyomavirus infection and persistence modelled in skin organoids
Merkel cell polyomavirus can infect and persist in skin cells, evading the immune system, but certain treatments can control it.
research Engineering a 3D wounded skin equivalent to study early inflammatory and regenerative responses in vitro
A 3D skin model helps study wound healing better than traditional methods.
research 1250 Development of an ex vivo human skin explant model to examine candidate gene functions in the hair follicle and epidermis
The model can effectively test gene functions and drug responses in human skin.
research 837 From genotoxic stresses to skin damage: Distinct, novel mechanisms of skin and hair damage in chemo/radiation therapy
Chemotherapy and radiation therapy cause skin and hair damage by altering gene expression and signaling pathways.
research Touch Receptors Undergo Rapid Remodeling in Healthy Skin
Touch sensitivity in mouse skin decreases during hair growth due to changes in touch receptors.
research Telemedicine Alopecia Assessment: Highlighting Patients With Skin of Color
Telemedicine is effective for diagnosing hair loss, especially in people with darker skin, during the pandemic.
research Thyroid Autoimmunity in Patients with Skin Disorders
People with alopecia areata often have thyroid autoimmunity.
research Cytotoxic Evaluation of Hair Relaxers and Straighteners Actives in Human-Derived Skin Cells
Hair relaxers and straighteners can be toxic to skin cells.
research Congenital cataract and slowly progressing facial skin lesions in a 5‐year‐old boy
A 5-year-old boy has Nevus Comedonicus Syndrome, causing skin lesions and a cataract.
research Guidelines of care for superficial mycotic infectionsof the skin: Tinea capitis and tinea barbae
Treat scalp and beard fungal infections early with oral antifungal medication and sometimes topical therapy, avoiding unnecessary allergy tests and surgery.
research Reply to: “Response to ‘Rethinking biotin therapy for hair, nail, and skin disorders’”
Biotin treatment for hair, nail, and skin disorders has weak evidence and should not be recommended unless new research shows clear benefits.
research New Frontiers of Non‐Invasive Detection in Scalp and Hair Diseases: A Review of the Application of Novel Detection Techniques
New non-invasive techniques can improve diagnosis and treatment of scalp and hair diseases.
research Birt–Hogg–Dubé syndrome: from gene discovery to molecularly targeted therapies
New therapies for Birt–Hogg–Dubé syndrome are being developed based on understanding the FLCN gene's role.
research Keratin‐based particles for protection and restoration of hair properties
Keratin-based particles safely improve hair strength, smoothness, and heat protection.
research A new hair follicle-derived human epidermal model for the evaluation of sunscreen genoprotection
The new lab-grown skin model is good for testing sunscreen's protection against DNA damage from UV light.
research Caution in the time of rashes and COVID-19
Skin symptoms linked to COVID-19 are hard to confirm, and more testing is needed to identify which are truly caused by the virus.
research Drug eruptions in dermatology
Skin reactions to drugs are common and can be deadly, usually requiring stopping the drug and may be better prevented with genetic testing in the future.
research Histocultures and Their Use
Histocultures help personalize cancer treatments, study hair growth, and explore immune responses.
research Expanding the Clinical and Mutational Spectrum of Recessive AEBP1-Related Classical-Like Ehlers-Danlos Syndrome
The study concludes that mutations in the AEBP1 gene can cause a form of Ehlers-Danlos syndrome and should be considered in diagnosis.
research Organoid‐Guided Precision Medicine: From Bench to Bedside
Organoid technology is improving personalized medicine by better predicting drug responses and treatments.
research In vitro models to study hair follicle generation
Scientists can now grow hair-like structures in a lab using special 3D culture systems, which could potentially help people with hair loss or severe burns.
research Contact Dermatitis Caused by Topical Minoxidil: Case Reports and Review of the Literature
Minoxidil can cause skin reactions, so testing is important for those with side effects.
research Multiple basal cell carcinomas in a patient with myotonic dystrophy type 1
A man with myotonic dystrophy type 1 had 28 skin cancers, suggesting a link between the disease and skin cancer, emphasizing the need for sun protection and regular skin checks.
research Lifting the biofilm lid on the antibacterial and antibiofilm effects of sodium hypochlorite against Staphylococcus aureus in atopic dermatitis
Sodium hypochlorite can effectively prevent and remove Staphylococcus aureus biofilms in atopic dermatitis at high enough concentrations.
research Mechanistic perspectives on the dermatologic potential of topical metformin: A scoping review
Topical metformin shows promise for skin treatments but needs more testing for safety and effectiveness.
research Scalp condition improvement with botanical extracts possessing chemical and physical antioxidant activity
Botanical extracts can improve scalp health by reducing oxidative stress.
research 231 Novel protocol for the invitro maintenance and expansion of adult epidermal LGR5+ stem cells
A new method helps grow skin stem cells better, which could improve skin grafts for burn victims.
research Hypersensitivity Diseases
The document concludes that various hypersensitivity diseases in horses can be diagnosed and treated with methods like immunotherapy and medication, and early aggressive treatment is crucial for severe diseases like equine cutaneous pythiosis.