11 citations
,
September 1997 in “Archives of Dermatology” Reduced androgens linked to kinky hair disorder and hair loss; 5a-reductase inhibitors may help.
25 citations
,
June 2022 in “Clinical and Experimental Dermatology” Menopause significantly affects skin health and conditions.
16 citations
,
November 2005 in “Journal of Clinical Pathology” CD1d expression in scalp skin and hair follicles changes with the hair cycle and may help protect against microbes.
January 2026 in “Forum Dermatologicum” Polycystic ovary syndrome (PCOS) is a complex disorder characterized by hormonal and metabolic dysregulation, with dermatological manifestations often serving as early indicators. This review highlights that the majority of PCOS patients experience skin-related symptoms, with hirsutism affecting about 70% of women, correlating with androgen levels and BMI. Androgenic acne is present in around 40% of patients, while androgenic alopecia affects 5–15%. Acanthosis nigricans is also noted, though its prevalence is less defined. The skin effectively reflects hormonal imbalances in PCOS, aiding in diagnosis and treatment.
46 citations
,
May 1995 in “Proceedings of the National Academy of Sciences” A specific gene region can control targeted and responsive gene expression in mice, useful for skin disorder treatments.
January 2025 in “Zenodo (CERN European Organization for Nuclear Research)” Collagen supplements may modestly improve skin and joint health, but effects on metabolism and blood sugar are inconsistent.
January 2025 in “Zenodo (CERN European Organization for Nuclear Research)” Collagen supplements may improve skin and joint health but have inconsistent effects on blood sugar and heart health.
17 citations
,
October 2021 in “Cellular & Molecular Biology Letters” New biomarkers and potential treatments for skin diseases were identified.
January 2024 in “Frontiers in immunology” Histone modification is key in treating chronic inflammatory skin diseases.
57 citations
,
February 2018 in “Journal of the American Academy of Dermatology” Biotin supplements are not proven to improve hair or nails and may interfere with medical tests.
3 citations
,
January 2021 in “Skin appendage disorders” Hair loss due to scalp metastasis from breast cancer, known as Neoplastic Alopecia, has a better survival rate than other scalp metastases and requires a biopsy for diagnosis.
24 citations
,
July 2018 in “Stem cells” Runx1 controls fat-related genes important for normal and cancer cell growth, affecting skin and hair cell behavior.
159 citations
,
December 2007 in “American Journal of Pathology” Stress-related substance P may lead to hair loss and negatively affect hair growth.
February 2023 in “Pakistan Journal of Medical and Health Sciences” Pregnancy can cause various skin changes, with stretch marks, dark lines on the abdomen, and skin darkening being the most common.
22 citations
,
May 2011 in “American Journal of Clinical Dermatology” Recognizing and managing skin-related psychiatric disorders in children is crucial for effective treatment.
11 citations
,
July 2012 in “Current Opinion in Pediatrics” Skin problems can be signs of hormone-related disorders and recognizing them early is important for treatment.
2 citations
,
October 2021 in “Journal of skin and stem cell” Nail disorders are often related to jobs like housework and manual labor, with cosmetic issues being the main concern, and are commonly caused by skin diseases like psoriasis.
August 2021 in “Journal of the American Academy of Dermatology” The study evaluated how alopecia areata severity relates to its psychosocial effects on patients.
17 citations
,
November 2012 in “Journal of Investigative Dermatology” The document concludes that over 500 genes are linked to hair disorders and this knowledge is important for creating new treatments.
5 citations
,
December 2011 in “Drug Research” CB-03-01 is a promising skin cream for treating hormone-related skin problems without causing harmful body-wide effects.
September 2017 in “Journal of Investigative Dermatology” Researchers created human cells that can turn into sebocytes, which may help study and treat skin conditions like acne.
1 citations
,
August 2000 in “Expert Opinion on Therapeutic Patents” Boosting mitochondrial energy production with supplements like acetyl-L-carnitine may improve aging-related cellular function and health conditions.
March 2014 in “Hair transplant forum international” A man experienced skin death after a hair transplant, likely due to poor blood supply related to his smoking habit.
7 citations
,
December 1981 in “International Journal of Dermatology” Understanding genes can help diagnose and treat skin color disorders.
7 citations
,
January 1986 in “Prenatal Diagnosis” Fetal skin biopsy can help diagnose protein-related disorders before birth.
218 citations
,
December 2011 in “Advances in Urology” The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.
128 citations
,
September 2011 in “British Journal of Dermatology” Obesity is linked to various skin problems and may increase the risk of skin cancer.
6 citations
,
October 2020 in “Endocrine journal” A patient with Werner syndrome showed a range of aging-like symptoms and metabolic issues, underscoring the need for early detection and treatment.
1 citations
,
December 2023 in “Frontiers in Behavioral Neuroscience” UVB exposure increases appetite by activating p53 in skin cells.
20 citations
,
January 2005 in “Australasian Journal of Dermatology” A woman had a skin condition with increased normal elastic fibers, not related to other known disorders, likely due to aging.