June 2023 in “Plastic and Reconstructive Surgery – Global Open” Exosomes may improve skin, scars, hair growth, and fat grafts in plastic surgery, but more research is needed.
Activin A and follistatin control when ear hair cells form in mice.
34 citations
,
June 2005 in “Developmental dynamics” Runx3 helps determine hair shape.
Iron deficiency worsens inflammatory skin diseases by disrupting iron balance and increasing inflammation.
9 citations
,
April 2022 in “Cell Communication and Signaling” High S100A4 levels worsen glioblastoma by promoting blood vessel growth.
131 citations
,
March 2004 in “The American journal of pathology” Modulating BMP activity changes the number, size, shape, and type of ectodermal organs.
Chemicals and stem cells combined have advanced regenerative medicine with few safety concerns, focusing on improving techniques and treatment effectiveness.
174 citations
,
April 2005 in “The American journal of pathology (Print)” Capsaicin, found in chili peppers, can slow down hair growth by affecting skin cells and hair follicles.
111 citations
,
June 2002 in “The EMBO Journal” Too much Smad7 can cause serious changes in skin tissues, including problems with hair growth, thymus shrinkage, and eye development issues.
31 citations
,
September 2013 in “Stem Cells” Smad1 and Smad5 are essential for hair follicle development and stem cell sleepiness.
6 citations
,
January 2013 in “Chemical & pharmaceutical bulletin/Chemical and pharmaceutical bulletin” A new compound shows promise as a topical treatment for hair loss.
1 citations
,
December 2019 in “Journal of medicine and life science” Docosahexaenoic acid (DHA) may help hair growth by promoting dermal papilla cell proliferation.
23 citations
,
November 2020 in “Central-European Journal of Immunology/Central European Journal of Immunology” Alopecia areata, a type of hair loss, is likely an autoimmune disease with a genetic link, but its exact cause is still unknown.
6 citations
,
November 2018 in “Histochemistry and Cell Biology” Mongolian gerbils heal wounds differently than mice, with unique protein levels and gene expression that affect skin repair.
January 2025 in “Scripta Medica” PDO, PLLA, and PCL threads increase collagen in ageing skin but don't change MMP1 gene expression.
22 citations
,
November 2024 in “Planta” Aromatic plants can naturally help prevent skin aging and improve skin health.
21 citations
,
October 2013 in “Molecular Biology of the Cell” The protein CCN2 controls hair growth by affecting hair follicle formation and stem cell activity in mice.
16 citations
,
July 2019 in “Journal of Cellular Biochemistry” Wnt7a protein is crucial for development and tissue maintenance and plays varying roles in diseases and potential treatments.
3 citations
,
September 2005 in “Experimental dermatology” The cornified envelope is crucial for skin's barrier function and involves key proteins and genetic factors.
1 citations
,
January 2019 in “Journal of Embryology & Stem Cell Research” MSCs help rejuvenate skin by promoting cell growth and reducing inflammation.
February 2026 in “MedScien” Mesenchymal stem cells can help delay skin aging and improve wound healing.
February 2026 in “Plastic and Aesthetic Research” Regenerative aesthetic medicine aims to restore tissue function, but needs more consistent evidence and standardized practices.
September 2023 in “Frontiers in cell and developmental biology” Vav2 changes how hair follicle stem cells' genes work as they age, which might improve regeneration but also raise cancer risk.
89 citations
,
January 2009 in “Advances in Clinical Chemistry” Fetal skin heals without scarring due to unique cells and processes not present in adult skin healing.
68 citations
,
December 2014 in “Cell Biochemistry and Function” Nuclear hormone receptors play a significant role in skin wound healing and could lead to better treatment methods.
56 citations
,
February 2012 in “Cell Cycle” MicroRNAs are crucial for controlling skin development and healing by regulating genes.
28 citations
,
July 2007 in “Development” TAF4 is important for skin cell growth and helps prevent skin cancer in mice.
15 citations
,
September 2007 in “Cell & tissue research/Cell and tissue research” Embryonic and adult stem cells are valuable for improving skin grafts and cell therapy.
13 citations
,
March 2022 in “Cell Death and Differentiation” Sema3A can both slow and speed up wound healing, depending on its form and combination with EGF.
5 citations
,
May 2020 in “Dermatologic Therapy” 5-alpha reductase inhibitors might worsen lung recovery in COVID-19 patients, suggesting a pause in their use.