12 citations
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December 2010 in “Journal of thoracic oncology” New treatments for non-small cell lung cancer are being tested, with some already in use, focusing on immune response and targeting cancer cells, but side effects vary.
56 citations
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January 1996 in “Journal of Forensic Sciences” Dye enters hair at the edges of cuticle cells and penetrates more from water than alcohol-based solutions.
43 citations
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November 2012 in “Pharmaceutical research” Fractional CO2 laser treatment significantly boosts drug and nanoparticle skin absorption, especially through hair follicles.
11 citations
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April 2023 in “Frontiers in Pharmacology” Integrating biological networks improves drug repurposing and ADR prediction.
7 citations
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March 2021 in “Molecular Medicine Reports” A mix of specific inhibitors and a growth factor helps keep hair growth cells from losing their properties in the lab.
6 citations
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January 2025 in “RSC Medicinal Chemistry” Targeting the RAAS with small molecules can improve cardiovascular disease treatments.
1 citations
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April 2017 in “Journal of Investigative Dermatology” SM04554 may increase hair growth as a topical treatment for androgenetic alopecia.
March 2026 in “Communications Biology” Certain compounds can boost hair and nail growth.
February 2024 in “Pharmaceutical research” Hair follicles affect how well small molecules can pass through the skin, and this varies depending on the molecule's features.
A molecule called α-ketobutyrate was found to extend lifespan and improve aging-related symptoms in worms and mice by activating certain cellular pathways and may help develop anti-aging treatments for humans.
113 citations
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September 2005 in “Journal of Investigative Dermatology” Applying a special compound can promote hair growth without harmful side effects.
6 citations
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March 2023 in “Frontiers in Cellular and Infection Microbiology” Golvatinib shows promise as a treatment for Omicron in elderly patients.
3 citations
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April 2022 in “International Journal of Molecular Sciences” Scientists turned mouse skin cells into hair-inducing cells using chemicals, which could help treat hair loss.
Hit15 shows promise as a COVID-19 treatment by reducing virus infection and inflammation.
November 2023 in “Bioorganic Chemistry” Drugs targeting the Androgen Receptor are effective for treating prostate cancer and other androgen-related conditions.
June 2024 in “Research Square (Research Square)” Aminoacridine and Minoxidil together show promise for better hair and nail growth.
47 citations
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November 2021 in “Advanced Functional Materials” The new hydrogel dressing with natural molecules helps heal wounds faster and improves skin repair.
63 citations
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May 2011 in “Clinical cancer research” The topical inhibitor CUR61414 was not effective in treating basal cell carcinoma in human trials.
11 citations
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February 2023 in “British Journal of Pharmacology” Isoxazole 9 (ISX9) may help regrow hair by activating certain cell signals.
9 citations
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March 2017 in “Journal of Visualized Experiments” The assay effectively identifies compounds that affect immune cell activation.
8 citations
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July 2023 in “Frontiers in Pharmacology” Cepharanthine shows promise as a COVID-19 treatment.
ISX9 helps regrow hair by activating a specific cell signaling pathway.
The treatment was ineffective in humans.
January 2025 in “Biochemical Pharmacology” Peficitinib can turn human fibroblasts into cells that help grow hair.
January 2024 in “SSRN Electronic Journal”
21 citations
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July 2022 in “Orphanet journal of rare diseases” New treatments for ichthyosis, like protein replacement and gene therapy, show promise and may become standard care.
140 citations
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November 2018 in “Pharmacology & Therapeutics” Using drugs to activate the Wnt/β-catenin pathway has potential for treating diseases but also presents challenges.
112 citations
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January 2014 in “Molecular and cellular therapies” Blocking the Wnt pathway could lead to new treatments for cancer and tissue repair but requires careful development to avoid side effects.
94 citations
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June 2016 in “The FASEB Journal” The Wnt/β-catenin pathway helps tissue regeneration but can also cause fibrosis, and drugs that inhibit this pathway may aid in healing skin and heart tissues.
89 citations
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November 2017 in “Journal of Cellular Physiology” The Wnt/β-catenin pathway is important for tissue development and has potential in regenerative medicine, but requires more research for therapeutic use.