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Prostate cancer cells can make their own androgens to activate the androgen receptor, and treatments like abiraterone may increase this ability, suggesting new therapies should target the entire steroid-making pathway.

Cells from balding scalps have more androgen receptors than cells from non-balding scalps.

The mutated hairless gene causes hair loss by acting as a new type of corepressor affecting thyroid hormone receptors.

The document concludes that adenosine receptor agonists have potential for treating various conditions, but only a few are approved due to challenges like side effects and the need for selective activation.

Estrogen Receptor ß (ERß) is the main hormone controller in human skin and hair follicles, not Estrogen Receptor α (ERα) or the Androgen Receptor (AR).

Hair follicles produce and respond to melatonin, affecting hair growth and sensitivity to estrogen.

Fibroblast growth factor receptor signaling controls cell development and repair, and its malfunction can cause disorders and cancer, but it also offers potential for targeted therapies.

Lowering testosterone speeds up wound healing in male mice.

A new mutation in the human glucocorticoid receptor reduces its function and causes resistance to glucocorticoids.

Minoxidil boosts hair growth by targeting adenosine and possibly sulfonylurea receptor 2B.

A three-month treatment with a GnRH agonist significantly lowered androgen levels and 5α-reductase activity in men with benign prostatic hyperplasia.

Skin has specialized touch receptors that can tell different sensations apart.

The three estrogen receptor genes are highly expressed in zebrafish neuromasts during development.

Prolactin affects when mice shed and grow hair.

A protein called CBP is found in prostate cancer and can increase the effectiveness of certain prostate cancer treatments.

The document concludes that targeting the androgen receptor may be a promising breast cancer treatment, especially for certain types.

Prostaglandin D2 blocks new hair growth after skin injury through the Gpr44 receptor.

Androgen receptors are key for development and health, affecting conditions like prostate cancer and male pattern baldness.

A new protein was made to detect specific skin cell growth receptors and worked in normal skin but not in skin cancer cells.

Hair sensitivity to androgens is partly controlled by specific enzyme expressions in different hair areas.

Blocking the prolactin receptor might help treat various diseases, but more research is needed.

Mice lacking fibromodulin have disrupted healing patterns, leading to abnormal skin repair and scarring.

Touch sensitivity in mouse skin decreases during hair growth due to changes in touch receptors.

LPA3 is crucial for embryo implantation and links LPA to prostaglandin signaling.

Androgen receptor signaling causes early aging of cells important for hair growth by damaging their DNA.

Testing for CAG repeat polymorphism in the androgen receptor gene is not currently recommended for managing hypogonadism.

NcoA4 may have roles beyond helping control gene activity, possibly affecting cell behavior and stability.

Mutations in certain receptors can cause diseases and offer new treatment options.

Spironolactone harms fish reproduction and is more potent in fish than invertebrates, needing environmental monitoring.

Oral contraceptives lower testosterone levels in women, especially those with certain genetic traits, and may be linked to increased breast cancer risk.