40 citations
,
January 2016 in “Elsevier eBooks” The skin is the largest organ, protecting the body, regulating temperature, and producing hormones.
37 citations
,
April 2017 in “npj Regenerative Medicine” PDGF signaling is crucial for maintaining and renewing hair follicle stem cells, which could help treat hair loss.
32 citations
,
January 1994 in “Skin Pharmacology and Physiology” Minoxidil helps hair growth by activating enzymes in hair follicles.
31 citations
,
January 2017 in “Advances in Experimental Medicine and Biology” Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.
26 citations
,
January 1978 in “Nephron” Minoxidil lowers blood pressure effectively but may cause side effects.
25 citations
,
February 2012 in “The Journal of Sexual Medicine” Finasteride reduces corpus cavernosum weight but doesn't affect erectile response in rats.
24 citations
,
April 2012 in “Developmental Biology” Dermal papillae cells, important for hair growth, come from multiple cell lines and can be formed by skin cells, regardless of their origin or hair cycle phase. These cells rarely divide, but their ability to shape tissue may contribute to their efficiency in inducing hair growth.
23 citations
,
June 1996 in “Toxicology” Older rats more affected by minoxidil's cardiotoxic effects than younger rats.
23 citations
,
March 1988 in “Biochemical Pharmacology” Minoxidil stops cells from making prostacyclin, which may help with hair growth. More research is needed.
21 citations
,
September 2001 in “Graefes Archive for Clinical and Experimental Ophthalmology” Minoxidil may help prevent capsular opacification after cataract surgery.
18 citations
,
February 2022 in “Cell Death Discovery” ECM1-modified stem cells can effectively treat liver cirrhosis.
17 citations
,
May 1975 in “Clinical Pharmacology & Therapeutics”
14 citations
,
December 2020 in “Journal of Investigative Dermatology” Aging causes changes in the scalp that can affect hair growth and lead to older-looking hair in women.
14 citations
,
April 2009 in “Acta Medica Scandinavica” Minoxidil helps control blood pressure but has side-effects, so it's not for everyone.
13 citations
,
February 2020 in “Cold Spring Harbor Perspectives in Biology” New methods have helped find cells that create other cells in the body.
13 citations
,
August 2013 in “Journal of pharmaceutical sciences” Researchers created a skin patch that delivers two drugs for treating enlarged prostate, which may improve patient use and dosage control.
11 citations
,
January 1995 in “Biomedicine & pharmacotherapy” TURP is the best treatment for BPH, but some patients prefer medications like alpha-blockers and finasteride.
10 citations
,
February 2009 in “European urology. Supplement” Treatment for benign prostatic hyperplasia involves drugs that either quickly relieve symptoms or reduce prostate size, with a combination offering more benefits but more side effects.
9 citations
,
March 2024 in “Journal of Biomaterials Applications” Rizatriptan benzoate-loaded dissolving microneedles are effective and convenient for treating acute migraines.
9 citations
,
January 2017 in “Elsevier eBooks” Skin's epithelial stem cells are crucial for repair and maintenance, and understanding them could improve treatments for skin problems.
8 citations
,
August 2011 in “Journal of Medicinal Food” D-004 may be a natural alternative to finasteride for treating enlarged prostate and male baldness.
7 citations
,
January 2016 in “Case reports in pediatrics” A girl with Becker's nevus syndrome showed good improvement in breast development using spironolactone.
6 citations
,
July 2015 in “Journal of Investigative Dermatology” Chicken feather gene mutation helps understand human hair disorders.
5 citations
,
July 2016 in “Journal of Clinical Hypertension” Men with severe early-onset baldness may have worse heart artery function and stiffer arteries if they have high blood pressure.
5 citations
,
January 2016 in “Journal of The American Academy of Dermatology” Skin doctors should know about skin and kidney disease links to prevent serious kidney problems.
4 citations
,
September 2015 in “Case Reports” A man fainted and felt unwell after using a strong hair growth product, but got better when he stopped using it.
3 citations
,
January 2022 in “PLoS ONE” The amnion bilayer dressing improved healing and reduced scarring in full-thickness burns.
2 citations
,
February 2020 in “Journal of Investigative Surgery” Flutamide-induced hypospadias in rats slows down early wound healing.
2 citations
,
January 2004 in “Medical Hypotheses” Hidden fungal infections might cause heart disease and clogged arteries.
1 citations
,
January 2019 in “Advances in Medical Sciences” The combination of azelaic acid, minoxidil, and caffeine significantly increased the survival of skin flaps by affecting certain body channels and nitric oxide levels.