89 citations
,
November 2014 in “International Journal of Nanomedicine” Using nanostructured lipid carriers to deliver spironolactone could improve treatment for hair loss.
87 citations
,
August 2017 in “Scientific Reports” The nanofiber scaffolds improved skin wound healing by supporting cell growth and tissue repair.
86 citations
,
February 2009 in “Journal of Neuroscience” Pregnancy increases certain GABAA receptors in rat brains, influenced by steroid levels.
86 citations
,
July 1990 in “British Journal of Pharmacology” Diazoxide, minoxidil sulphate, and cromakalim relax rat blood vessels by opening K+ channels, with some differences in their actions.
86 citations
,
April 2016 in “Nature Communications” Notch1 helps skin heal by attracting specific immune cells.
84 citations
,
July 2003 in “European journal of biochemistry” Mouse skin can produce and process serotonin, with variations depending on hair cycle, body location, and mouse strain.
84 citations
,
February 2013 in “Clinica chimica acta” Hair mineral analysis might help diagnose diseases early, but standard methods are needed.
84 citations
,
March 2010 in “Infectious Disease Clinics of North America” The document concludes that rapid identification, isolation, and strict infection control are crucial to manage SARS outbreaks.
84 citations
,
April 2005 in “Dermatologic Clinics” Treatments for melanin disorders exist, but more effective options needed.
83 citations
,
June 2020 in “Materials & Design” Sponge helps heal wounds faster with less inflammation and better skin/hair growth.
82 citations
,
August 2006 in “Pharmacology, Biochemistry and Behavior” Certain steroids in the brain affect mood and symptoms of depression, and treatments targeting these steroids show promise for improving these symptoms.
82 citations
,
October 2019 in “Frontiers in Immunology” Changes to the Foxp3 protein affect how well regulatory T cells can control the immune system, which could help treat immune diseases and cancer.
81 citations
,
January 2006 in “Journal of cellular physiology” Mice without the vitamin D receptor gene lose hair due to disrupted hair follicle cycles.
81 citations
,
November 2012 in “Journal of the National Cancer Institute” The tumor suppressor gene FLCN affects mitochondrial function and energy use in cells.
80 citations
,
March 2008 in “Contact Dermatitis” Nearly half of the French individuals surveyed reported having a sensitive scalp, more common in women, often linked to hair loss and symptoms like itching, and triggered by factors including shampoos and pollution.
77 citations
,
August 2025 in “Signal Transduction and Targeted Therapy” Extracellular vesicles show promise for treating diseases but face challenges in development and regulation.
77 citations
,
June 2007 in “PLoS ONE” Birds can regenerate inner ear cells using specific gene pathways, unlike mammals.
77 citations
,
January 2015 in “International Journal of Biological Macromolecules” Chitosan nanoparticles improve minoxidil delivery to hair follicles for better alopecia treatment.
76 citations
,
July 2019 in “Scientific Reports” Baicalin nanocapsules greatly enhance its anticancer effects on breast cancer cells.
75 citations
,
May 2013 in “Journal of the American Academy of Dermatology” Zinc deficiency in children can cause skin issues and can be serious if not diagnosed and treated properly.
73 citations
,
June 2010 in “PLoS Genetics” A gene mutation in mice causes hair loss, weak bones, and protein buildup, showing how protein processing issues can lead to diseases.
72 citations
,
December 2012 in “Expert Opinion on Drug Delivery” Niosomes are promising for skin drug delivery, offering benefits like improved drug penetration and stability.
70 citations
,
December 2004 in “Differentiation” The study identified and characterized new keratin genes linked to hair follicles and epithelial tissues.
69 citations
,
August 1999 in “Developmental biology” The nude gene causes skin cell overgrowth and improper development, leading to hair and urinary issues.
68 citations
,
May 2021 in “Endocrine” People with diabetes or obesity should manage their conditions carefully as they have a higher risk of severe COVID-19.
68 citations
,
September 2018 in “International Journal of Molecular Sciences” Air pollution (PM10) increases skin inflammation and aging by reducing collagen and may trigger a repair response in skin cells.
68 citations
,
March 2002 in “Journal of pharmaceutical sciences” Nonionic liposomes are the best for delivering genes to skin cells.
67 citations
,
January 2022 in “Theranostics” Advanced nanocarrier and microneedle drug delivery methods are more effective, safer, and less invasive for treating skin diseases.
67 citations
,
December 2019 in “PloS one” Beta-caryophyllene helps improve wound healing in mice, especially in females.
67 citations
,
June 2018 in “Engineering in Life Sciences” Plant cell culture is a promising method for creating sustainable and high-quality cosmetic ingredients.