153 citations
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November 2004 in “Current Medicinal Chemistry” The document concludes that Catalyst software is effective for drug design, identifying potent compounds for various medical conditions.
20 citations
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September 2005 in “Endocrinology” Certain changes to the B-ring of androgen receptor ligands can increase their effectiveness for potential treatments of muscle and bone conditions.
7 citations
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August 2019 in “Bioorganic & medicinal chemistry” Analog 23 is a promising compound for prostate cancer treatment.
11 citations
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December 2010 in “Journal of Inclusion Phenomena and Macrocyclic Chemistry” Finasteride's solubility and bioavailability improved by forming solid dispersions and inclusion complexes.
12 citations
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January 2009 in “Journal of Oleo Science” Sterol surfactants can effectively dissolve UV ray absorbers.
9 citations
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November 2017 in “International Journal of Nanomedicine” Tiny particles called anionic squarticles can effectively remove a common antidepressant from the body after an overdose.
February 2024 in “Journal of Molecular Structure” The new minoxidil and salicylic acid hydrogel improves alopecia treatment.
1 citations
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October 2025 in “Gels” Nanogels with hydrophobic modifications improve oral drug delivery for intestinal disease treatment.
Cepharanthine and tetrandrine show promise as COVID-19 drugs.
Deep eutectic solvents can replace toxic solvents in extracting useful compounds for medicines.
28 citations
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April 2008 in “Journal of Inclusion Phenomena and Macrocyclic Chemistry” Minoxidil mixed with β-cyclodextrin improves solubility and gradual release.
December 2025 in “Brazilian Journal of Chemical Engineering”
1 citations
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September 2022 in “Sudan Journal of Medical Sciences” Danoprevir, remdesivir, and saridegib may effectively inhibit SARS-CoV-2.
June 2024 in “International Journal of Pharmaceutical Research and Applications” Minoxidil tablets with 6% croscarmellose sodium dissolve quickly and work well.
111 citations
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August 2002 in “Journal of Medicinal Chemistry” New compounds were made that block an enzyme linked to breast cancer better than existing treatments.
3 citations
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November 2017 in “International Journal of Cosmetic Science” Solute binding to hair keratin is mainly driven by hydrophobic interactions and changes with pH.
Encapsulating hair loss drugs in cyclodextrins improves their solubility and reduces scalp irritation.
7 citations
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February 2019 in “Journal of Molecular Liquids” Minoxidil dissolves better in propylene glycol and water as temperature and propylene glycol amount increase.
Different crystal forms of drugs can change their effectiveness.
13 citations
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May 2011 in “Bioorganic & Medicinal Chemistry” Changing the 6-position on benzopyran molecules affects insulin release, with some compounds showing strong inhibitory effects.
38 citations
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November 2016 in “Aaps Pharmscitech” Nanoparticles with more oleic acid improved the delivery and stability of the drug spironolactone.
16 citations
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November 2018 in “Medicinal Chemistry” The compound GD-23 may reduce anxiety like diazepam by targeting the TSPO receptor.
Self-assembling peptide hydrogels effectively deliver drugs locally, enhancing treatment and reducing side effects.
129 citations
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January 2004 in “Journal of medicinal chemistry” Researchers developed new compounds that target the androgen receptor effectively with fewer side effects.
May 2023 in “Journal of Pharmaceutical Innovation” May 2010 in “Europe PMC (PubMed Central)” Near-infrared probes can safely and effectively image cysteine protease activity for disease diagnosis.
23 citations
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June 2017 in “Drug Design Development and Therapy” Cyclodextrins improve finasteride's solubility and bioavailability for hair loss treatment.
16 citations
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July 2015 in “Journal of Molecular Structure” Finasteride crystals are held together by hydrogen bonds and weak interactions, forming synthon pseudopolymorphs.
3 citations
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August 2022 in “Pharmaceuticals” Solidified SEDDS improve drug stability and bioavailability better than liquid SEDDS.
16 citations
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June 2015 in “Drug Design Development and Therapy” The new formulation improves dutasteride's absorption when taken orally.