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research MICRO-MORPHOMETRIC STUDY OF SKIN IN DEVELOPING HUMAN FETUSES AND ITS CLINICAL RELEVANCE
Understanding fetal skin development helps diagnose congenital skin diseases.
research BMP-FGF Signaling Axis Mediates Wnt-Induced Epidermal Stratification in Developing Mammalian Skin
Wnt signaling is essential for forming the skin's spinous layer through a BMP-FGF pathway.
research 0932 Spatiotemporal gradient of mesenchymal stiffness controls sweat gland morphogenesis
Tissue stiffness affects sweat gland development by guiding cell differentiation through specific signals.
research Twist2 contributes to skin regeneration and hair follicle formation in mouse fetuses
Twist2 is essential for proper skin healing and hair growth in developing mice.
research Cloning and induced differentiation of skin stem cells in vitro
Skin stem cells can become different cell types, like hair or bone cells, in lab conditions.
research Fine structure and immunocytochemistry of monotreme hairs, with emphasis on the inner root sheath and trichohyalin‐based cornification during hair evolution
Monotreme hair structure and protein distribution are similar to other mammals, but their inner root sheath cornifies differently, suggesting a unique evolution from reptile skin.
research Expression of Type II Collagen at the Middle Stages of Chick Embryonic and Human Fetal Skin Development
research Skin tissue engineering
Improved understanding of stem cell mechanisms can enhance skin tissue engineering.
research Joint Public Review: Touch receptor end-organ innervation and function require sensory neuron expression of the transcription factor Meis2
Meis2 is essential for touch sensation and nerve function in mice.
research The development of cutaneous afferent pathways in fetal sheep: a structural and functional study
Fetal sheep develop skin nerve pathways and responses to touch and heat between 75 and 134 days of gestation.
research Murine skin-derived multipotent papillary dermal fibroblast progenitors show germline potential in vitro
Mouse skin cells can become sperm-like cells in the lab.
research Tracing the developmental origin of tissue stem cells
Tissue stem cells originate from specific areas in organs and are vital for organ maintenance and repair.
research Generation and characterization of hair-bearing skin organoids from human pluripotent stem cells
Scientists created hair-growing skin models from stem cells, which could help treat hair loss and skin diseases.
research Identification of Somatic KRAS Mutation in a Korean Baby with Nevus Sebaceus Syndrome
A Korean baby with nevus sebaceus syndrome was found to have a KRAS gene mutation.
research Live imaging of stem cell and progeny behaviour in physiological hair-follicle regeneration
Hair regeneration needs dynamic cell behavior and mesenchyme presence for stem cell activation.
research Estrogen-Dependent Ontogeny of Sex Differences in Somatostatin Neurons of the Hypothalamic Periventricular Nucleus*
Male rats have more somatostatin neurons than females due to testosterone converting to estrogen during early development.
research Tail Tales: What We Have Learned About Regeneration from Xenopus Laevis Tadpoles
Xenopus laevis tadpoles can regenerate complex tail structures, offering insights for regenerative medicine.
research Two cases of aplasia cutis congenita with hair collar signs and macrophage hyperplasia
Two cases showed skin abnormalities without bone or neural defects.
research Skin Cell Heterogeneity in Development, Wound Healing, and Cancer
Different types of skin cells play specific roles in development, healing, and cancer.
research Bioengineered skin organoids: from development to applications
Scientists have improved 3D models of human skin for research and medical uses, but still face challenges in perfectly replicating real skin.
research Developmental and evolutionary comparative analysis of a regulatory landscape in mouse and chicken
Gene regulation evolved differently in mouse and chicken skin, but remained stable in their trunks.
research Skin Appendage Proteins of Tetrapods: Building Blocks of Claws, Feathers, Hair and Other Cornified Epithelial Structures
Understanding proteins in skin structures like claws and hair is crucial for future research.
research Characterization and Localization of Side Population Cells in Mouse Skin
Mouse skin has special cells in the epidermis that decrease with age and are linked to keratinocyte stem cells.
research 0882 Patterning and regional specification of hairy skin
Secreted inhibitors of Wnt and IGF signaling control hair and tooth development, creating species-specific patterns.
research Shaping epithelial tissues by stem cell mechanics in development and cancer
research Characterization of the epidermal-dermal junction in hiPSC-derived skin organoids
The study created hair-bearing skin models that lack a key protein for skin layer attachment, limiting their use for certain skin disease research.
research Structural and Immunocytochemical Characterization of Keratinization in Vertebrate Epidermis and Epidermal Derivatives
Vertebrate skin evolved to be more specialized and complex, especially in land animals.
research Synchronizing actin and microtubules for axonal branching
Certain proteins help nerve cells branch, and other findings relate to cancer, stem cell behavior, and cell division.
research MIM and Cortactin Antagonism Regulates Ciliogenesis and Hedgehog Signaling
MIM is crucial for hair follicle formation and regeneration by controlling cilia formation and hedgehog signaling through its interaction with Cortactin and Src.