18 citations
,
November 2016 in “PeerJ” Human hair follicles can be used to create stem cells that might help clone hair for treating hair loss or helping burn patients.
1 citations
,
August 2021 Biomimetic dermal papilla spheres can help regenerate hair to some extent.
1 citations
,
January 2021 in “Processes” Researchers successfully grew horse skin cells that produce pigment from hair follicle samples.
December 2025 in “Preprints.org” Aging dermal papilla cells can be reprogrammed for potential hair growth and skin repair.
December 2025 in “FEBS Open Bio” Long-term skin biopsy cultures can produce many fibroblasts that remain functional and can be reprogrammed.
June 2022 in “Research Square (Research Square)” Nestin-expressing cells turn into a specific type of skin cell in hair follicles during development and in adults.
8 citations
,
March 2015 in “International Journal of Oncology” Tsc2-deficient stem cells can help understand and treat TSC-related tumors.
173 citations
,
August 2015 in “Developmental cell” The study identified unique genes in hair follicle cells and their environment, suggesting these genes help organize cells for hair growth.
80 citations
,
September 2007 in “Cell Cycle” Stem cells in hair follicles can become various cell types, including neurons.
18 citations
,
May 2023 in “Science Advances” Activating the sonic hedgehog pathway in chicken embryos can permanently change scales to feathers.
14 citations
,
February 2022 in “The Journal of clinical investigation/The journal of clinical investigation” Scientists made a mouse model of a serious skin cancer by changing skin cells with a virus and a specific gene, which is similar to the disease in humans.
11 citations
,
October 2021 in “Frontiers in Cell and Developmental Biology” Non-coding RNAs are important for hair growth and could lead to new hair loss treatments, but more research is needed.
10 citations
,
August 2021 in “Frontiers in cell and developmental biology” Scientists made structures that look like human hair follicles using stem cells, which could help grow hair without using actual human tissue.
5 citations
,
October 2022 in “BMC genomics” Certain microRNAs are important for sheep hair follicle development and could help improve wool quality.
October 2025 in “Animals” miR-200a reduces goose fibroblast growth by targeting PITX2 in the Wnt pathway.
May 2024 in “Cell proliferation” Melatonin helps hair grow by activating a specific signaling pathway.
1 citations
,
September 2021 in “Pharmaceutics” High-dose finasteride may help treat glioblastoma but needs localized delivery for effectiveness.
7 citations
,
January 2022 in “Biomedicines” Cells from the lower part of hair follicles are a promising, less invasive option for immune system therapies.
667 citations
,
May 2008 in “Genes & Development” Histone demethylases can change gene expression and may be linked to diseases like cancer.
6 citations
,
July 2016 in “Cell cycle/Cell cycle (Georgetown, Tex. Online)” Younger mice's hair-follicle stem cells are better at turning into heart cells than older mice's.
25 citations
,
February 2019 in “Genomics” Cashmere and milk goats have different hair growth cycles and gene expressions, which could help improve wool production.
81 citations
,
September 2013 in “PLoS ONE” Primary and secondary hair follicle cells in Cashmere goats have different gene expressions affecting hair growth and size.
8 citations
,
November 2020 in “Frontiers in Cell and Developmental Biology” Certain genes are more active in baby scalp cells and can help grow hair when added to adult mouse skin cells.
3 citations
,
August 2014 in “Cellular reprogramming” Hair follicle stem cells need all reprogramming factors to become pluripotent.
21 citations
,
July 2018 in “International Journal of Molecular Sciences” Foxn1 is crucial for skin development and healing, and altering its expression may aid regenerative medicine.
1 citations
,
April 2018 in “Journal of Investigative Dermatology” PRC1 is essential for proper skin development and stem cell formation by controlling gene activity.
September 2019 in “The journal of investigative dermatology/Journal of investigative dermatology” Tet1/2/3 enzymes affect hair follicle cell development by influencing BMP signaling.
April 2018 in “Journal of Investigative Dermatology” Researchers found that the Leptin receptor is a consistent marker for hair follicle dermal cells, which may help future hair research.
138 citations
,
June 2012 in “Genes & Development” Sonic hedgehog signaling is crucial for hair growth and maintaining hair follicle identity.
5 citations
,
April 2018 in “Journal of Dermatological Science” Adjusting estradiol-ANGPT2 levels can promote hair growth in female pattern hair loss.