research Haplotypes spanning centromeric regions reveal persistence of large blocks of archaic DNA
Ancient DNA blocks are still present in human genomes, possibly due to advantages they provide.
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90-120 / 1000+ results research Expanding the Scope of a Dynamic Perspective on Positive Adolescent Sexual Development
Adolescent sexual development should focus on positive aspects, including biological, psychological, and contextual factors, and recognize individual differences and the role of pleasure.
research Genetic and biochemical aspects of the synthesis of keratin by hair follicles
Gene expression regulates keratin production for normal hair growth.
research Does topical minoxidil at concentrations higher than 5% provide additional clinical benefit?
Using more than 5% minoxidil can help hair growth more, but results vary and side effects may increase.
research Advances in Longevity: The Intersection of Regenerative Medicine and Cosmetic Dermatology
Cosmetic dermatology is improving with new technologies but faces ethical and regulatory challenges.
research Keratin Promotes Differentiation of Keratinocytes Seeded on Collagen/Keratin Hydrogels
Keratin helps skin cells mature when added to a collagen mix, which could be important for skin and hair health.
research Platelet-derived extracellular vesicles promote hair follicle growth through β-catenin signaling pathway
Platelet-derived extracellular vesicles can boost hair growth by activating a specific signaling pathway.
research Recent progress of polymeric microneedle-assisted long-acting transdermal drug delivery
Polymeric microneedles offer a less invasive, long-lasting drug delivery method that improves patient compliance and reduces side effects.
research Skin Cell Heterogeneity in Development, Wound Healing, and Cancer
Different types of skin cells play specific roles in development, healing, and cancer.
research Hair regrowth in alopecia areata patients following Stem Cell Educator therapy
Stem Cell Educator therapy helps regrow hair and improve life quality in alopecia areata patients.
research Finasteride nano-transferosomal gel formula for management of androgenetic alopecia: ex vivo investigational approach
NTF gel improves finasteride delivery for hair loss treatment, reducing side effects.
research Data-driven strategies for drug repurposing: insights, recommendations, and case studies
Data-driven methods can effectively identify existing drugs for new uses, especially in cancer, infections, and respiratory diseases.
research Exosomes in Dermatology: Emerging Roles in Skin Health and Disease
Exosomes could improve skin health and treat skin diseases, but more research is needed.
research Stimulation of Stem Cell Niches and Tissue Regeneration in Mouse Skin by Switchable Protoporphyrin IX-Dependent Photogeneration of Reactive Oxygen Species In Situ
Controlled light treatment in mouse skin speeds up healing and hair growth.
research Hoxc13/β-catenin Correlation with Hair Follicle Activity in Cashmere Goat
Hoxc13 is linked to seasonal hair growth in Cashmere goats and is affected by melatonin.
research Severe hypoalbuminemia in patient with pulmonary edema and pleural effusion: a case report
Hypoalbuminemia can cause pleural effusion and needs careful treatment.
research Rat steroid 5α-reductase kinetic characteristics: Extreme pH-dependency of the type II isozyme in prostate and epididymis homogenates
The activity of a specific rat enzyme in the prostate and epididymis is highly dependent on the acidity level.
research National Lipid Association Recommendations for Patient-Centered Management of Dyslipidemia: Part 2
The guidelines suggest lifestyle changes, diet adjustments, and personalized medication to manage dyslipidemia and reduce heart disease risk.
research Liposomal systems as drug delivery vehicles for dermal and transdermal applications
Liposomal systems show promise for delivering drugs through the skin but face challenges like high costs and stability issues.
research Differential activity of 2-methylene-19-nor vitamin D analogs on growth factor gene expression in rhino mouse skin and comparison to all-trans retinoic acid
Some vitamin D analogs can thicken skin and reduce pore size like a common acne treatment, with one analog also affecting skin growth factors.
research Challenges in treatment of patients with non-classic congenital adrenal hyperplasia
Treating non-classic congenital adrenal hyperplasia is complex because the benefits of hormone treatment must be weighed against potential health risks.
research Mucosal TLR5 activation controls healthspan and longevity
Activating TLR5 in the gut can extend lifespan and improve health in aged mice.
research Measurement of Serum Prolactin Level in Vitiligo Patients and its Correlation with Prolactin Gene Polymorphism
Prolactin levels and gene polymorphism are not linked to vitiligo severity but are related to BMI.
research <p>Potential of Nanoparticles as Permeation Enhancers and Targeted Delivery Options for Skin: Advantages and Disadvantages</p>
Nanoparticles can improve skin drug delivery but have challenges like toxicity and stability that need more research.
research Niosomes as a vesicular carrier for topical administration of minoxidil: formulation and in vitro assessment
Niosomes improve minoxidil skin penetration for hair loss treatment.
research Androgens and Cardiovascular Disease
Male hormones may play a role in the development of heart disease, and more research is needed to understand their effects.
research Antagonism of NMDA receptors as a potential treatment for Down syndrome: a pilot randomized controlled trial
Memantine may slightly improve memory in people with Down syndrome, but more research is needed.
research Environmental stress but not subjective distress in children or adolescents with alopecia areata
Kids with alopecia areata may experience more stress but not necessarily feel more anxious or depressed than others.
research Sex hormones modulate pathogenic processes in experimental traumatic brain injury
Sex hormones affect brain injury differently in males and females.
research The Role of Non-Aromatizable Testosterone Metabolite in Metabolic Pathways
Normal levels of DHT can reduce belly fat and increase muscle, but too much can lead to hair loss, prostate issues, and possibly heart disease.