8 citations
,
April 2012 in “Laser Physics Letters” Antiseptic particles penetrate deeper into hair follicles than non-antiseptic ones.
3 citations
,
April 2015 in “International research journal of pharmacy” Gentamicin penetrates pig skin better through open hair follicles than blocked ones.
3 citations
,
March 2005 in “Iranian Journal of Pharmaceutical Sciences” Liposomes and niosomes can increase finasteride retention in the skin.
13 citations
,
September 2011 in “International Urology and Nephrology” November 2005 in “CRC Press eBooks” SEPA 0009 is a promising and safe skin penetration enhancer for topical use.
January 2022 in “Advanced Pharmaceutical Bulletin” Clove oil and grape seed extract increase finasteride skin absorption, while urea decreases it.
18 citations
,
October 2019 in “Advanced Pharmaceutical Bulletin” Microemulsions can improve skin delivery of finasteride.
26 citations
,
December 2022 in “Future Journal of Pharmaceutical Sciences” Invasomes with natural terpenes can improve drug delivery through the skin.
1 citations
,
January 2012 in “CINECA IRIS Institutial research information system (University of Pisa)” 15 citations
,
March 2015 in “PloS one” Scientists restored fertility in male mice lacking a key fertility gene by using a modified gene.
161 citations
,
April 2006 in “Journal of Investigative Dermatology” Liposomes with certain properties can effectively deliver drugs deep into hair follicles.
January 2017 in “Isan Journal of Pharmaceutical Sciences” A 3:1 surfactant mixture in microemulsions can effectively deliver finasteride through the skin.
31 citations
,
January 2001 in “PubMed”
27 citations
,
April 2011 in “Folia Histochemica et Cytobiologica” DHT deficiency can disrupt cell connections in rat testes, possibly affecting fertility.
82 citations
,
January 2002 in “Journal of drug targeting” Drugs penetrate scalp skin better than abdominal skin, with scalp hair follicles aiding in higher drug delivery.
April 2016 in “International Journal of Drug Delivery” The ethosomal formulation improved finasteride delivery through the skin.
14 citations
,
January 2020 in “Biomaterials Science” Created microspheres show potential for safe and effective use in prostate artery embolization.
74 citations
,
June 2010 in “European Journal of Pharmaceutics and Biopharmaceutics” Minoxidil foam enters hair follicles and skin for hair growth.
14 citations
,
October 1977 in “The Lancet” 1 citations
,
January 2007 in “Zhōnghuá yàoxué zázhì” Ethosomes deliver finasteride through the skin more effectively than liposomes.
54 citations
,
October 2002 in “Journal of controlled release” Medium lipophilic substances penetrate skin best, and adding ethanol can increase delivery to hair follicles.
1 citations
,
July 2017 in “Microscopy and Microanalysis” Iron oxide nanoparticles mainly enter the skin through hair follicles and sebocytes, not the dermis.
12 citations
,
March 2012 in “ATLA. Alternatives to laboratory animals” Hair follicles significantly affect the skin absorption of some drugs.
2 citations
,
May 2006 in “Journal of Separation Science” The method effectively measures spermidine in hair lotions.
Hair follicles can effectively absorb nano-sized particles, making them potential targets for localized drug delivery.
39 citations
,
November 2013 in “European journal of pharmaceutics and biopharmaceutics” Massage increases how deep both rigid and flexible liposomes can go into skin, with flexible ones going deeper, and covering the skin (occlusion) helps rigid ones more.
82 citations
,
January 1994 in “Skin Pharmacology and Physiology” Hair follicles and glands significantly increase steroid absorption in skin.
12 citations
,
June 2011 in “Journal of applied polymer science” L-phenylalanine and hydrolyzed eggwhite protein deeply penetrate human hair.
94 citations
,
May 2011 in “BJCP. British journal of clinical pharmacology/British journal of clinical pharmacology” Hair follicles greatly increase caffeine absorption through the skin shortly after it's applied.
26 citations
,
May 2012 in “Pharmaceutical Development and Technology” PEVs effectively deliver minoxidil through skin.