November 2022 in “Journal of the Endocrine Society” A transman experienced lasting virilization symptoms after stopping testosterone, which were resolved with estradiol treatment.
6 citations
,
April 2009 in “Fertility and Sterility” Finasteride helps induce ovulation in nonresponder PCOS women.
36 citations
,
June 2014 in “PLOS ONE” Finasteride, a hair loss drug, may cause long-term sexual side effects due to changes in hormone receptor levels.
6 citations
,
July 2018 in “Steroids” Testosterone changes how certain channels work in male rat reproductive tracts, affecting fertility-related fluid balance.
February 2024 in “BIOspektrum” Genetic research may lead to better ways to predict and treat male-pattern hair loss.
44 citations
,
January 2006 in “Biological & Pharmaceutical Bulletin” Androgen hormones cause hair follicle scarring in hair loss, and finasteride helps reduce it.
7 citations
,
April 2000 in “Archives of Pathology & Laboratory Medicine” 16 citations
,
July 2021 in “American Journal of Medical Genetics Part A” Mutations in the LSS gene cause hair loss and may affect brain development, with varying severity.
19 citations
,
September 2019 in “PLOS genetics” Telomere damage affects skin and hair follicle stem cells by messing up important growth signals.
September 2024 in “Electronic Journal of General Medicine” Diagnosing Sertoli-Leydig cell tumors is challenging due to their unusual symptoms and can occur at any age.
36 citations
,
July 1988 in “Archives of Dermatological Research” Pili annulati is caused by a protein metabolism disorder affecting hair structure.
47 citations
,
January 2021 in “Fertility and Sterility” COVID-19 might affect male fertility, but more research is needed to understand the full impact.
8 citations
,
March 2010 in “The journal of investigative dermatology/Journal of investigative dermatology” The 14-3-3σ gene is essential for preventing hair loss.
November 2024 in “Asian Journal of Biological Sciences” High consumption of avocado leaves harms male fertility.
6 citations
,
June 2012 in “Physiology” The document concludes that more research is needed to understand airway repair and to improve tissue engineering for lung treatments.
29 citations
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July 2012 in “The Journal of Sexual Medicine” Rats had lasting erectile problems after stopping a certain medication.
October 2017 in “Journal of The European Academy of Dermatology and Venereology” Stem cells preservation in AGA could be a potential therapy, but more cases needed.
43 citations
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December 2008 in “Molecular biology of the cell” Disrupting Smad4 in mouse skin causes early hair follicle stem cell activity that leads to their eventual depletion.
Finasteride harms Daphnia magna's reproduction and metabolism.
8 citations
,
March 2015 in “International Journal of Oncology” Tsc2-deficient stem cells can help understand and treat TSC-related tumors.
12 citations
,
March 2023 in “The FASEB Journal” Platelet-rich plasma can improve erectile function in older individuals by reducing prostate enlargement.
May 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” The enzyme 5α-reductase is important for proper blood vessel development during the fertility-related transformation of the uterus lining.
694 citations
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April 2000 in “Nature genetics” Msx2 deficiency in mice leads to bone growth and organ development problems.
1 citations
,
January 2010 in “uO Research (University of Ottawa)” Atrazine and finasteride disrupt hormone signaling and affect frog development.
105 citations
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January 2004 in “The Journal of Urology” Finasteride improves chronic pelvic pain, saw palmetto doesn't.
September 2013 in “Nature Reviews Urology” 309 citations
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June 2001 in “Molecular and Cellular Endocrinology” Mutations in the androgen receptor gene cause androgen insensitivity, leading to female traits in genetically male individuals.
5 citations
,
September 2011 in “Andrologia” Finasteride use may be linked to rare testicular tumor, but more research needed.
October 1999 in “The Journal of Urology” New treatments and diagnostic methods for urological conditions show promise, but some lack sufficient accuracy for clinical use.
18 citations
,
July 2020 in “Basic and Clinical Andrology” Wait 3 months after COVID-19 before trying assisted reproduction and further research is needed on COVID-19's effects on male hormones and fertility.