1 citations
,
November 2005 in “Journal of Andrology” The meeting highlighted promising genetic treatments for male fertility issues but noted concerns about certain cancer risks and ICSI safety.
3 citations
,
April 2002 in “Animal Science” Spermidine injections increased wool growth rate in lambs without changing fibre thickness.
48 citations
,
December 2019 in “Reproductive Biology and Endocrinology” More research is needed to confirm sperm DNA fragmentation as a reliable tool for diagnosing male infertility.
January 2025 in “MEDS Public Health and Preventive Medicine” Spermidine supplements can help extend the hair growth phase and may be useful for treating hair loss.
54 citations
,
May 2001 in “Journal of Investigative Dermatology” Excessive putrescine causes hair loss in transgenic mice by disrupting hair follicle development.
1 citations
,
December 2011 in “EFSA Journal” Spermidine may help extend the growth phase of hair.
305 citations
,
March 2008 in “AJP Endocrinology and Metabolism” SSAT is a key enzyme affecting cell growth and metabolism, with potential but risky use in disease treatment.
37 citations
,
February 2005 in “Journal of Investigative Dermatology” Overexpression of SSAT causes hair loss and skin issues, but reducing putrescine can help.
January 2020 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” More research is needed to make sperm DNA fragmentation a reliable tool for diagnosing male infertility.
13 citations
,
September 2011 in “International Urology and Nephrology” April 2026 in “ACS Applied Materials & Interfaces” Sper-12 nanoparticles may help treat hair loss by delivering siRNA to target androgen receptors.
2 citations
,
August 2021 in “The Journal of Urology” The procedure involving seminal vesiculoscopy, TURED, and balloon dilation effectively treated a man's hematospermia and improved his dysorgasmia.
June 2014 in “The Journal of Urology” April 2022 in “The Journal of Sexual Medicine” Treating hematospermia can improve sexual function and reduce anxiety.
13 citations
,
July 2015 in “Archives of dermatological research” N1-methylspermidine helps hair growth and reduces inflammation in hair follicles.
43 citations
,
February 1999 in “Biochemical Journal” Overexpression of SSAT in mice causes hair loss, liver damage, and sensitivity to polyamine analogues.
61 citations
,
July 2011 in “PLOS ONE” Spermidine may help reduce hair loss and deserves further testing as a treatment.
6 citations
,
November 2018 in “Journal of molecular histology” Testosterone increases fluid secretion and aquaporin expression in the vas deferens, which is important for male fertility.
February 2015 in “Oxford University Press eBooks” 19 citations
,
March 2016 in “Frontiers in Plant Science” Spermidine is essential for plant growth and adaptation to stress.
September 2008 in “Fertility and Sterility” Men and women in infertile couples feel using donor sperm may cause more stress and marital issues than using donor eggs.
2 citations
,
November 2017 in “Histochemistry and Cell Biology” Polyamines are abundant in certain parts of rat hair follicles and may play a key role in hair growth.
October 2025 in “Physiologia” Spermidine may improve skin health and hair growth by enhancing cell function.
February 2026 in “Applied Biosciences” The study found potential new DNA patterns in fertility genes, but further testing is needed.
17 citations
,
May 2021 in “Journal of Cell Science” N1-acetylspermidine promotes hair follicle stem cell self-renewal.
91 citations
,
July 2004 in “Journal of Biological Chemistry” Overexpressing SSAT enzyme reduces prostate tumor growth in mice.
1 citations
,
October 2024 in “BMJ Case Reports” Fertility-preserving surgery can help women with early-stage Sertoli-Leydig cell tumors conceive naturally.
16 citations
,
March 2020 in “Animal Biotechnology” Transgenic sheep embryos with a specific promoter were successfully created, but more research is needed for gene expression in hair follicles.
20 citations
,
January 2021 in “GeroScience” Spermidine helps protect against aging by preserving telomere length.
A stable sheep ovarian cell line was created for studying reproduction and hormones.