6 citations
,
January 2020 in “Skin Pharmacology and Physiology” HIF-1α stimulators, like deferiprone, work as well as popular hair loss treatments, minoxidil and caffeine, in promoting hair growth.
3 citations
,
January 2019 in “Advances in stem cells and their niches” Dermal papilla cells are key for hair growth and color, influencing hair type and size, and their interaction with stem cells could help treat hair loss and color disorders.
18 citations
,
October 2021 in “Journal of Advanced Research” A new tissue engineering method could greatly improve hair regeneration therapies.
April 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” Researchers developed a method to grow human hair follicles using 3D-printed skin models and modified cells.
July 2024 in “International Journal of Molecular Sciences” The inhibitor DPP can promote hair growth.
1 citations
,
September 2019 in “Journal of Investigative Dermatology” Human hair matrix cells and dermal papilla fibroblasts can form early hair follicle structures but don't produce hair shafts yet.
61 citations
,
September 2016 in “NPG Asia Materials” Glycol chitosan hydrogels enable quick, safe 3D cell spheroid formation for various applications.
The method effectively creates uniform, viable cell spheroids for 3D cell culture.
January 2020 in “Open University of Cape Town (University of Cape Town)” Efficient culture methods are needed to keep human keratinocytes undifferentiated for hair follicle induction.
13 citations
,
September 2021 in “Frontiers in Cell and Developmental Biology” Suspension culture is best for stem cell differentiation into endoderm cells.
1 citations
,
December 2023 in “Scientific reports” 3D microenvironments in microwells improve hair follicle stem cell behavior and hair regeneration.
October 2013 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” Three-dimensional culture helps dermal papilla cells grow new human hair follicles.
45 citations
,
January 2022 in “Lab on a Chip” The platform effectively grows lung cancer cell spheroids for drug testing.
125 citations
,
March 2017 in “Micromachines” Microfluidic technology improves cell spheroid creation for better drug testing and tissue engineering.
62 citations
,
February 2016 in “ACS Applied Materials & Interfaces” Technique creates 3D cell spheroids for hair-follicle regeneration.
5 citations
,
November 2024 in “Cells” Fish cell spheroids are a promising tool for replicating real-life conditions in research.
November 2025 in “Bioengineering” The new method may improve skin grafts and hair growth.
July 2020 in “Research Square (Research Square)” A 3D co-culture model improved stem cell function and wound healing.
26 citations
,
August 2016 in “ACS Applied Materials & Interfaces” A boronic acid copolymer quickly forms cell clusters, useful for tissue and tumor modeling.
8 citations
,
May 2024 in “ACS Applied Materials & Interfaces” PCL nanoscaffold-based liver spheroids are effective for drug screening and studying liver toxicity.
April 2016 in “Journal of Investigative Dermatology” Removing alkaline phosphatase from human skin cells hinders the creation of new hair follicles.
June 2020 in “Journal of Investigative Dermatology” Scientists successfully grew mini hair follicles using human skin cells, which could help treat baldness.
April 2016 in “Journal of Investigative Dermatology” Scientists have found a way to grow hair follicles from human cells in a lab, which could help treat hair loss and skin damage.
3 citations
,
February 2021 in “Experimental dermatology” Dermal papilla microtissues could be useful for initial hair growth drug testing.
51 citations
,
May 2019 in “Biomaterials” Researchers developed a method to grow hair follicles using special beads that could help with hair loss treatment.
12 citations
,
April 2022 in “Journal of Bioscience and Bioengineering” Activating the PI3K/Akt pathway improves hair growth by human dermal papilla cells in hair beads.
44 citations
,
June 2018 in “Journal of Cellular Physiology” Researchers developed a 3D model of human hair follicle cells that can help understand hair growth and test new hair loss treatments.
July 2025 in “bioRxiv (Cold Spring Harbor Laboratory)” A new Wnt surrogate specifically targets the Frizzled7 receptor, promoting organoid formation and hair growth.
4 citations
,
January 2021 in “Archives of dermatological research” The study created a new model to better understand human hair growth and health.
August 2023 in “Cell Proliferation” Human cells in plasma-derived gels can potentially mimic hair follicle environments, improving hair regeneration therapies.