Proper niche formation in Drosophila requires Slit-Robo signaling for cell migration.
April 2023 in “ACS Biomaterials Science & Engineering” 3D scaffolds mimicking the extracellular matrix are crucial for effective hair follicle regeneration.
35 citations
,
April 2008 in “Human Molecular Genetics” Skin and hair can help us understand organ regeneration, especially how certain stem cells might be used to form new organs.
19 citations
,
November 2012 in “Cell Communication and Signaling” FGF-9 speeds up the early development of certain organs, showing potential for organ regeneration.
November 2022 in “Journal of Investigative Dermatology” Growing dermal papilla cells in 3D improves their ability to help form new blood vessels.
16 citations
,
November 2020 in “In Vitro Cellular & Developmental Biology - Animal” Microfollicles can effectively model human hair follicles for research and testing.
61 citations
,
December 2016 in “The EMBO Journal” The study showed that hair follicle stem cells can maintain and organize themselves in a lab setting, keeping their ability to renew and form hair and skin.
January 2006 in “Chinese Journal of Dermatology” Hair follicle-like structures can be created using hair cells on collagen/chitosan scaffolds.
27 citations
,
January 2006 in “Colloids and Surfaces B: Biointerfaces” Researchers found that bulge cells from human hair can grow quickly in culture and have properties of hair follicle stem cells, which could be useful for skin treatments.
44 citations
,
July 2016 in “Stem Cells Translational Medicine” Scientists discovered that certain stem cells from mice and humans can be used to grow new hair follicles and skin glands when treated with a special mixture.
1 citations
,
June 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” Reprogramming 3D environments can create hair follicles in the lab.
3 citations
,
September 2018 in “Journal of Biomaterials Science, Polymer Edition” Different materials affect the growth of brain cells and fibroblasts, with matrigel being best for brain cell growth.
4 citations
,
October 2004 in “Humana Press eBooks” Epidermal growth factor stops hair follicle formation in developing mouse skin.
129 citations
,
May 2015 in “Cell Stem Cell” Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.
64 citations
,
January 2013 in “The journal of investigative dermatology/Journal of investigative dermatology” Human stem cells can help form hair follicles in mice.
18 citations
,
November 2013 in “Molecules and Cells” New culture method keeps human skin stem cells more stem-like.
12 citations
,
January 2025 in “Nature Reviews Molecular Cell Biology”
12 citations
,
August 2016 in “Current opinion in genetics & development” Organs like hair follicles can renew themselves in complex ways, adapting to different needs and environments.
58 citations
,
November 2012 in “PLoS ONE” Human skin cells can be turned into versatile stem cells, but their ability to do so decreases with repeated use.
4 citations
,
May 2012 in “Tissue Engineering and Regenerative Medicine” Scientists created three types of structures to help regrow hair follicles, and all showed promising results for hair regeneration.
63 citations
,
April 2010 in “Development” Compartmentalized organization might be crucial for stem cells to effectively respond to growth or injury.
26 citations
,
May 2011 in “Tissue Engineering Part A” Hydrogel surface properties affect mouse embryoid body differentiation.
4 citations
,
November 2024 in “Current Opinion in Genetics & Development” January 2011 in “Hispania Judaica bulletin” Mechanical forces are crucial for hair regeneration in skin organoids.
August 2023 in “Scientific reports” Human stem cells were turned into cells similar to those that help grow hair and showed potential for hair follicle formation.
January 2019 in “Institutional Repositories DataBase (IRDB)” Hair follicles and skin structures were successfully regenerated in the lab using specific cell arrangements and mechanical conditions.
2 citations
,
January 2009 in “Human cell culture”
51 citations
,
May 2021 in “Nature Communications” High proliferation and cell delamination drive early skin development, while later stages may not rely on cell division orientation.
January 2026 in “Advanced Healthcare Materials” The new bioreactor improves skin grafts by evenly stretching cells and monitoring conditions for better growth.
January 2022 in “Institutional Repositories DataBase (IRDB)” Pen-type microwells are best for forming hair follicle germ structures.