research Bioinspired tuning of glycol chitosan for 3D cell culture
Glycol chitosan hydrogels enable quick, safe 3D cell spheroid formation for various applications.
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research Melatonin’s effect on hair follicles in a goat (Capra hircus) animal model
Melatonin improved secondary hair growth in goats but didn't affect primary hair density or litter size.
research Dermal papilla cells and melanocytes response to physiological oxygen levels depends on their interactions
Low oxygen levels improve the function of hair and skin cells when they are in direct contact.
research Formulation of chloroaluminum phthalocyanine incorporated into PS-b-PAA diblock copolymer nanomicelles
The PS-b-PAA copolymer nanomicelles are effective for delivering a cancer treatment drug in photodynamic therapy.
research 773 Generation of human hair follicle organoids in vitro and ex vivo by co-culture of primary human hair matrix keratinocytes and dermal papilla fibroblasts
Scientists successfully grew mini hair follicles using human skin cells, which could help treat baldness.
research The Dermal Papilla: An Instructive Niche for Epithelial Stem and Progenitor Cells in Development and Regeneration of the Hair Follicle
The dermal papilla is crucial for hair growth and health, and understanding it could lead to new hair loss treatments.
research Inducing hair follicle neogenesis with secreted proteins enriched in embryonic skin
Three specific proteins can turn adult skin cells into hair-growing cells, suggesting a new hair loss treatment.
research The Effect of JAK Inhibitor on the Survival, Anagen Re-Entry, and Hair Follicle Immune Privilege Restoration in Human Dermal Papilla Cells
Ruxolitinib may help treat hair loss by reducing inflammation, promoting hair growth signals, and protecting hair follicle immunity.
research Generation of trichogenic adipose-derived stem cells by expression of three factors
Scientists made stem cells that can grow hair by adding three specific factors to them.
research 139 Anti-BCC efficacy of a topical hedgehog inhibitor without adverse effects in BCNS patients in a phase 2 randomized controlled trial
Topical patidegib gel effectively treats basal cell carcinoma in Gorlin syndrome patients without causing the side effects seen with oral treatments.
research Targeted delivery of extracellular vesicles: the mechanisms, techniques and therapeutic applications
Engineered extracellular vesicles show promise for targeted therapy but need more research for clinical use.
research A Mechanical-assisted Post-bioprinting Strategy for Challenging Bone Defects Repair
The new method improves bone repair by enhancing cell loading and stability in bioprinted scaffolds.
research 250 Sweat glands shrink upward with aging, causing dermal layer defects that lead to loss of skin elasticity and wrinkling-establishment of 3D imaging method for skin appendages
Aging causes sweat glands to shrink and move upward, leading to less elastic skin and more wrinkles.
research Mucocutaneous Manifestations of Endocrine Disorders
Skin symptoms can indicate endocrine disorders and have various treatments.
research Generating hair follicle inductive dermal papillae cells from adipose derived mesenchymal stem cells
Adipose-derived stem cells can be used to create cells that help grow new hair.
research Current Advances of Nanocarrier Technology-Based Active Cosmetic Ingredients for Beauty Applications
Nanocarrier technology in cosmetics improves ingredient delivery and effectiveness while reducing side effects.
research Stem cell-derived exosomes: emerging therapeutic opportunities for wound healing
Tiny vesicles from stem cells could be a new treatment for healing wounds.
research Trichoscopic Evaluation of the Effectiveness of Topical Stemoxydine for Hair Restoration in Androgenetic Alopecia: A Prospective Pre–Post Single‐Arm Exploratory Study
Topical Stemoxydine improves hair density in androgenetic alopecia with few side effects.
research Harnessing mesenchymal aggregation for engineered organ‐level regeneration: Recent progress and perspective
Scientists are using clumps of special stem cells to improve organ repair.
research Adaptive 3D Self‐Assembly of Colorectal Cancer Cells With Unchanged Tumor Phenotype and Drug Sensitivity
Colorectal cancer cells can adapt without losing their traits or drug sensitivity.
research Dermoscopy of Chronic Radiation-Induced Dermatitis in Patients with Head and Neck Cancers Treated with Radiotherapy
Dermoscopy can help assess the severity of chronic radiation-induced skin damage in head and neck cancer patients.
research Exosomes in Aesthetic Medicine: An Overview
Exosomes are promising tools in aesthetic medicine for skin and hair regeneration.
research Low-dose rapamycin microdepots promote hair regrowth via autophagy modulation
Low-dose rapamycin microdepots can help regrow hair by activating certain cell processes.
research 5-Fluorouracil induces hair loss by inhibiting β-catenin signaling and angiogenesis
5-Fluorouracil causes hair loss by blocking signals needed for hair growth.
research Scaffold-based developmental tissue engineering strategies for ectodermal organ regeneration
Scaffold-based strategies show promise for regenerating hair follicles and teeth but need more research for clinical use.
research A Multimodal Hair-Loss Treatment Strategy Using a New Topical Phytoactive Formulation: A Report of Five Cases
The new topical botanical formulation significantly regrew hair in all five patients without side effects.
research Centella asiatica L. Urb. Extracellular Vesicle and Growth Factor Essence for Hair and Scalp Health: A 56-Day Exploratory Randomized Trial
Centella asiatica with growth factors improves hair and scalp health.
research Melanocytes in regenerative medicine applications and disease modeling
Melanocytes are important for normal body functions and have potential uses in regenerative medicine and disease treatment.
research Clinical applications of exosomes in cosmetic dermatology
Exosomes could improve skin and hair treatments but are limited by cost, production difficulty, and need for more research.
research Bioengineered skin organoids: from development to applications
Scientists have improved 3D models of human skin for research and medical uses, but still face challenges in perfectly replicating real skin.