Dupilumab improved hair and skin in a woman with Netherton syndrome.
March 2026 in “bioRxiv (Cold Spring Harbor Laboratory)” Spiny mice have a unique skin structure that helps them heal and regenerate quickly.
Spiny mice have resilient, large mitochondria that help them regenerate tissue.
PCOS may be linked to spina bifida in young females.
June 2023 in “Dermatopathology” A woman had a unique skin growth with hair follicle, oil glands, fat cells, spindle cells, and nerve fibers.
June 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” A specific molecular switch, driven by MAPK/ERK signaling, helps spiny mice heal wounds by regenerating skin instead of forming scars.
June 2021 in “bioRxiv (Cold Spring Harbor Laboratory)” KIF18B is important for correctly positioning cell division machinery in skin cells, affecting hair follicle development.
Spiny keratoderma is a rare skin condition with small spines on palms and soles, possibly linked to abnormal hair formation.
April 2019 in “The journal of investigative dermatology/Journal of investigative dermatology” Spiny mice regenerate skin better than laboratory mice due to larger hair bulges, more stem cells, and different collagen ratios.
Deleting the MAD2L1 gene is tolerated in certain mouse cancer models.
Deleting the MAD2L1 gene in mice led to rapid tumor growth despite chromosomal instability.
NuMA-microtubule interactions are vital for proper skin structure formation and function.
January 2003 in “Zhongguo linchuang jiepouxue zazhi” Human hair keratin may help repair injured spinal cord tissue in rats.
January 2001 in “Zhongguo linchuang jiepouxue zazhi” Human hair keratin may help repair spinal cord injuries.
A man had temporary hair loss after a spinal cord injury, with some permanent thinning remaining.
418 citations
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September 2012 in “Nature” African spiny mice can regenerate skin, hair, and cartilage, but not muscle, and their unique abilities could be useful for regenerative medicine.
71 citations
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January 2011 in “Journal of cutaneous pathology” A rare skin condition was confirmed to be associated with a specific virus in a young girl.
55 citations
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May 2007 in “Australasian journal of dermatology” Two boys developed a viral skin infection during chemotherapy, which resolved with improved immune function.
40 citations
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November 2021 in “npj Regenerative Medicine” Adult spiny mice recover better from heart attacks than common lab mice.
39 citations
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June 2018 in “Burns” The spiny mouse can fully regenerate skin after burns, unlike the lab mouse.
33 citations
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November 2012 in “JAMA Dermatology” Most women with weird scalp feelings had neck spine problems, and some got better with gabapentin treatment.
28 citations
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November 2017 in “Molecular and cellular endocrinology” Testosterone and its byproducts help support male sexual behavior through different pathways in the brain and body.
26 citations
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December 1979 in “Journal of Cutaneous Pathology” Seborrheic keratoses may partly come from hair follicle cells.
25 citations
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September 1973 in “Archives of dermatology” Using tretinoin cream on the skin can get rid of hair plugs caused by Trichostasis spinulosa.
24 citations
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May 2018 in “Journal of Molecular Endocrinology” The spiny mouse is a unique menstruating rodent that can help us understand menstruation and reproductive disorders.
19 citations
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November 2018 in “Experimental Dermatology” The spiny mouse can regenerate its skin without scarring, which could help us learn how to heal human skin better.
19 citations
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March 2016 in “British journal of dermatology/British journal of dermatology, Supplement” Trichodysplasia spinulosa is a rare skin disease in immunocompromised patients caused by a specific virus targeting hair follicle cells.
17 citations
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December 1994 in “International Journal of Dermatology” Recognizing both trichostasis spinulosa and eruptive vellus hair cysts together is crucial for accurate diagnosis and treatment.
15 citations
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March 2014 in “Molecular Medicine Reports” α-spinasterol from Melandrium firmum can help reduce prostate enlargement.
15 citations
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August 2011 in “Lasers in medical science” The 755-nm alexandrite laser effectively and quickly treats trichostasis spinulosa with minimal pain and no side effects.