Epidermal stem cells help renew skin and heal wounds, influenced by specific proteins and markers.
109 citations
,
April 1997 in “Archives of Dermatological Research” Mast cell and nerve fiber interactions in mouse skin change with the hair cycle.
January 2007 in “The Year book of dermatology” Researchers successfully isolated and identified key stem cells in human hair follicles, which could help develop new skin and hair treatments.
28 citations
,
January 2013 in “Stem cells” Certain human skin cells marked by CD44 and ALDH are rich in stem cells capable of long-term skin renewal.
4 citations
,
February 2020 in “Cell & tissue research/Cell and tissue research” Hair follicle stem cells might help treat traumatic brain injury.
153 citations
,
October 2007 in “Cell Stem Cell” New research suggests that skin cell renewal may not require a special type of cell previously thought to be essential.
26 citations
,
September 2001 in “Journal of Investigative Dermatology” BSSP may help skin tumors grow and could be a marker or target for skin cancer treatment.
16 citations
,
February 2013 in “Molecular Medicine Reports” CD34+ cells from fat tissue help form hair follicles and blood vessels in skin.
72 citations
,
May 1993 in “The Journal of Cell Biology” Trichohyalin in sheep hair follicles may help with structure and calcium binding.
1 citations
,
November 2020 in “Biochemical Society transactions” Different types of skin stem cells can change and adapt, which is important for developing new treatments.
106 citations
,
September 2010 in “Stem cells” Skin-derived precursors in hair follicles come from different origins but function similarly.
68 citations
,
April 2014 in “Journal of Investigative Dermatology” Trichohyalin-like proteins are essential for the development of skin structures like hair, nails, and feathers.
3 citations
,
July 1990 in “PubMed” Human hair follicles can grow and form structures in a collagen gel, useful for studying hair cell growth.
27 citations
,
January 2006 in “Colloids and Surfaces B: Biointerfaces” Researchers found that bulge cells from human hair can grow quickly in culture and have properties of hair follicle stem cells, which could be useful for skin treatments.
January 2012 in “Journal of Investigative Dermatology” Small molecule DMF improves psoriasis and multiple sclerosis, adult skin cells can be made to grow new hair, certain skin cells initiate hair growth, IL-17C controls gut health and can cause skin inflammation, and skin cells produce IL-17 that can lead to psoriasis.
37 citations
,
May 2016 in “Scientific Reports” Combining skin cells with fat-derived stem cells can improve hair growth.
25 citations
,
October 2005 in “PubMed” Keratin 19 expression in certain skin cells is temporary and not a reliable stem cell marker.
233 citations
,
October 2004 in “Differentiation” Stem cells are in deep skin layers, while differentiating cells are in shallow layers.
75 citations
,
August 2011 in “Journal of Investigative Dermatology” Forming spheres boosts the ability of certain human cells to create hair follicles when mixed with mouse skin cells.
Rat hair follicle bulge cells can become nerve and glial cells, showing potential for neuroprotection.
26 citations
,
April 1996 in “Journal of Investigative Dermatology”
June 2021 in “Research Square (Research Square)” The exact identity of skin stem cells and how skin cells differentiate is not fully known.
January 2004 in “中国组织化学与细胞化学杂志”
18 citations
,
November 2020 in “Frontiers in Cell and Developmental Biology” Inflammation plays a key role in activating skin stem cells for hair growth and wound healing, but more research is needed to understand how it directs cell behavior.
31 citations
,
September 2016 in “PLoS ONE” Cell division orientation varies by body site and is linked to epidermal thickness and cell density.
151 citations
,
February 2006 in “Stem Cells and Development” Hair follicles can be a good source of stem cells like those from bone marrow.
16 citations
,
January 2018 in “Biochemical and Biophysical Research Communications” Researchers created five new human scalp cell lines that could be useful for hair growth and loss research.
January 2020 in “한국공업화학회 연구논문 초록집” Encapsulated hair cells in a special gel can help regenerate hair follicles, potentially treating hair loss.
September 2007 in “PubMed” Implanted human scalp cells can regenerate hair-like structures in mice.
238 citations
,
October 1994 in “Current opinion in genetics & development” The document concludes that recent research has improved understanding of skin diseases and the balance between cell growth and differentiation in the epidermis.