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Experimental Assessment of 3-Meta-Pyridine-1,2,4-Oxadiazole Deoxycholic Acid Derivative as a Prototype of 5-Alpha-Reductase Inhibitors in Silico and in Vivo Models

research Experimental Assessment of 3-meta-Pyridine-1,2,4-Oxadiazole Deoxycholic Acid Derivative as a Prototype of 5-α-Reductase Inhibitors in silico and in vivo Models

January 2023 in “Bioorganičeskaâ himiâ”

The new compound is a promising, less toxic alternative to finasteride for treating prostate issues.

research Pre-keratin isolated from epidermal microsomes

7 citations , December 1970 in “Biochimica et Biophysica Acta (BBA) - Protein Structure”

research Synthesis and biological activity evaluation of new isatin-gallate hybrids as antioxidant and anticancer agents (in vitro) and in silico study as anticancer agents and coronavirus inhibitors

3 citations , June 2024 in “Pharmacia”

New isatin-gallate hybrids show promise as antioxidants, cancer treatments, and coronavirus inhibitors.

research LB890 Cyclic hair growth requires spatiotemporal heterogeneity in hair follicle signaling network

July 2022 in “The journal of investigative dermatology/Journal of investigative dermatology”

Hair growth cycles need varied signals in space and time.

research Reaction of Finasteride Intermediate with Benzeneseleninic Anhydride: An In-Depth Study

2 citations , November 2008 in “Industrial & Engineering Chemistry Research”

Impure benzeneseleninic anhydride samples cause lower finasteride intermediate yields.

Synthesis and Biological Evaluation of Amino-Pyridines as Androgen Receptor Antagonists for Stimulating Hair Growth and Reducing Sebum Production

research Synthesis and biological evaluation of amino-pyridines as androgen receptor antagonists for stimulating hair growth and reducing sebum production

17 citations , August 2007 in “Bioorganic & Medicinal Chemistry Letters”

A compound made by Pfizer can potentially stimulate hair growth and reduce oil production, making it a good candidate for topical use.

research 17‐beta estradiol and prednisolone as potential stimulators of hair re‐growth in chemotherapy‐induced human hair follicle damage via ‘dystrophic catagen’ promotion?

June 2008 in “Experimental Dermatology”

17-beta estradiol and prednisolone may help regrow hair damaged by chemotherapy.

research Antifungal activity and phytochemical screening of Calotropis procera leaf extracts against some dermatophytes

2 citations , January 2023 in “International Journal of Dermatology Research”

Calotropis procera leaf extracts have antifungal properties, especially against Microsporum canis.

research Preparation of finasteride by selective dehydrogenation using IBX

January 2009 in “Chemical Reagents”

The method produces finasteride with a 92% yield.

research DIFFERENTIAL STRIPPING TECHNIQUE TO DETERMINE FINASTERIDE RETENTION IN HAIR FOLLICLES AFTER IN VITRO TOPICAL APPLICATION

January 2013 in “CINECA IRIS Institutial research information system (University of Pisa)”

research [Clinical findings with a low-dosed antiandrogene (cyproteronacetate) and aethinyloestradiol women with virilising symptoms (author's transl)].

3 citations , April 1977 in “PubMed”

The treatment improved acne, seborrhoea, and hirsutism, with some side effects like spotting and nervousness.

research Phytochemical and infra-radiation test of Mangkokan leaf (Nothophanax scutellarum merr.)

2 citations , February 2021 in “IOP Conference Series Earth and Environmental Science”

Mangkokan leaf contains various beneficial compounds like alkaloids, flavonoids, and steroids.

Efficacy and Safety of Diphenylcyclopropenone Alone or in Combination with Anthralin in the Treatment of Chronic Extensive Alopecia Areata: A Retrospective Case Series

research Efficacy and safety of diphenylcyclopropenone alone or in combination with anthralin in the treatment of chronic extensive alopecia areata: A retrospective case series

44 citations , February 2015 in “Journal of the American Academy of Dermatology”

Combining diphenylcyclopropenone with anthralin is more effective for hair regrowth in alopecia areata than using diphenylcyclopropenone alone, but may cause more side effects.

research Studies on synthesis of finasteride

January 2004 in “Zhōnghuá yàoxué zázhì”

The new method for making finasteride is cheaper and gives a higher yield.

research Pharmacognostic evaluation of Sphagneticola calendulacea (L.) Pruski: Leaves

May 2022 in “Journal of pharmacognosy and phytochemistry”

The evaluation of Creeping Daisy leaves found important characteristics and compounds that support its use in medicine.

research Thrombotic risk minimization for Diane‐35 and generics

7 citations , September 2017 in “Pharmacoepidemiology and Drug Safety”

The use of Diane-35 and its generics significantly decreased in the Netherlands.

4-(Alkylthio)- and 4-(Arylthio)-Benzonitrile Derivatives as Androgen Receptor Antagonists for the Topical Suppression of Sebum Production

research 4-(Alkylthio)- and 4-(arylthio)-benzonitrile derivatives as androgen receptor antagonists for the topical suppression of sebum production

11 citations , March 2009 in “Bioorganic & Medicinal Chemistry Letters”

Chemicals called 4-(alkylthio)- and 4-(arylthio)-benzonitrile derivatives can potentially reduce oil production on skin, which could help treat conditions like acne and hair loss.

research A new method for synthesis of finasteride

January 2011 in “Zhongguo xin yao zazhi”

A new, safer method to make finasteride from progesterone is effective for industrial use.

research CD44/TRPV1 dual-targeted nanocarrier enables drug retention and multidimensional therapy for inflammatory skin diseases

May 2026 in “Chemical Engineering Journal”

research Topical Cyperus rotundus essential oil for treatment of axillary hyperpigmentation: a randomized, double‐blind, active‐ and placebo‐controlled study

2 citations , October 2021 in “Clinical and experimental dermatology”

Cyperus rotundus essential oil effectively treats underarm darkening, reduces inflammation, and slows hair growth.

research Development and evaluation of crystalline inclusion complex of finasteride using electrospraying as a novel approach

2 citations , July 2020 in “Journal of Drug Delivery Science and Technology”

Created finasteride complex to increase water solubility and drug release.

Allergens of Permanent Hair Dyes Induce Epidermal Damage, Skin Barrier Loss, and IL-1 Alpha Increase in Epidermal In Vitro Model

research Allergens of permanent hair dyes induces epidermal damage, skin barrier loss and IL-1 α increase in epidermal in vitro model

12 citations , December 2017 in “Food and chemical toxicology”

Permanent hair dye mixtures can irritate and damage the skin.

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