October 1986 in “Inpharma” Spironolactone helps reduce hair growth in women with hirsutism but may cause menstrual irregularities.
November 1982 in “Inpharma” Spironolactone reduces hair growth in women with unexplained excessive hairiness.
April 2023 in “International Journal of Women's Dermatology” Spironolactone is safe for breast cancer survivors with alopecia and does not increase cancer risk.
March 2023 in “Current Pharmaceutical Design” Spironolactone is effective for idiopathic hirsutism but has limited effects on other PCOS symptoms.
November 2022 in “Al-Azhar International Medical Journal (Print)” Combining 5% spironolactone and 5% minoxidil is safe and more effective for treating hair loss.
September 2022 in “Journal of The American Academy of Dermatology” Monitoring potassium levels is important for women taking spironolactone.
September 2022 in “Journal of The American Academy of Dermatology” Dermatologists should monitor potassium levels in women taking spironolactone for acne, hair loss, and hirsutism.
September 2022 in “Journal of The American Academy of Dermatology” Older women taking spironolactone for hair loss may need yearly potassium checks due to a higher risk of hyperkalemia.
April 2021 in “Journal of Investigative Dermatology” Spironolactone safely and effectively treats hair loss in female scarring alopecia patients.
June 2020 in “The Medical Journal of Cairo University” Topical spironolactone works better than topical finasteride for hair loss.
October 2019 in “International Journal of Research in Dermatology” Combining minoxidil and spironolactone is more effective for female hair loss, but minoxidil alone is sufficient after 6 months.
May 2024 in “Reactions weekly”
August 2023 in “Journal of Cosmetic Dermatology” Both minoxidil-spironolactone and minoxidil-finasteride treatments work for hair loss, but minoxidil-spironolactone is slightly more effective, especially in women.
November 2020 in “Journal of The American Academy of Dermatology” Taking vitamin C and vitamin E twice a day can help prevent sunburn and DNA damage from UVB exposure.
46 citations
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January 2000 in “The Journal of Clinical Endocrinology and Metabolism” 24 citations
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December 2020 in “Kardiologiia” Bromhexine and spironolactone together reduced COVID-19 symptoms and hospitalization time without side effects.
4 citations
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January 2007 in “Iraqi postgraduate Medical Journal” April 2026 in “International Journal of Medical Arts” March 2009 in “Hair transplant forum international” 15 citations
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July 2021 in “AAPS PharmSciTech” January 2026 in “Mendeley Data” January 2026 in “Mendeley Data” October 2022 in “British Journal of Dermatology”
255 citations
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October 1985 in “The Journal of Clinical Endocrinology & Metabolism” Spironolactone treatment increases the amount of testosterone available in the body.
198 citations
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January 1998 in “Dermatology” The human sebocyte culture model has improved understanding of oily skin and acne, and how they can be treated.
169 citations
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August 2004 in “Baillière's best practice & research. Clinical obstetrics & gynaecology/Baillière's best practice and research in clinical obstetrics and gynaecology” Lower doses of treatments for hirsutism and acne in PCOS are effective and cause fewer side effects.
130 citations
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September 1990 in “Journal of the American Academy of Dermatology” Flutamide effectively reduced excessive hair growth and improved related symptoms in hirsutism patients without significant side effects.