November 2022 in “Al-Azhar International Medical Journal (Print)” Combining 5% spironolactone and 5% minoxidil is safe and more effective for treating hair loss.
September 2022 in “Journal of The American Academy of Dermatology” Monitoring potassium levels is important for women taking spironolactone.
September 2022 in “Journal of The American Academy of Dermatology” Dermatologists should monitor potassium levels in women taking spironolactone for acne, hair loss, and hirsutism.
September 2022 in “Journal of The American Academy of Dermatology” Older women taking spironolactone for hair loss may need yearly potassium checks due to a higher risk of hyperkalemia.
April 2021 in “Journal of Investigative Dermatology” Spironolactone safely and effectively treats hair loss in female scarring alopecia patients.
June 2020 in “The Medical Journal of Cairo University” Topical spironolactone works better than topical finasteride for hair loss.
January 2026 in “American Journal of Translational Research” The metoprolol-spironolactone combination improves heart function in patients with coronary heart disease and heart failure.
May 2024 in “Reactions weekly”
August 2023 in “Journal of Cosmetic Dermatology” Both minoxidil-spironolactone and minoxidil-finasteride treatments work for hair loss, but minoxidil-spironolactone is slightly more effective, especially in women.
November 2020 in “Journal of The American Academy of Dermatology” Taking vitamin C and vitamin E twice a day can help prevent sunburn and DNA damage from UVB exposure.
46 citations
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January 2000 in “The Journal of Clinical Endocrinology and Metabolism” 24 citations
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December 2020 in “Kardiologiia” Bromhexine and spironolactone together reduced COVID-19 symptoms and hospitalization time without side effects.
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January 2007 in “Iraqi postgraduate Medical Journal” 34 citations
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January 1995 in “The Journal of Clinical Endocrinology and Metabolism” April 2026 in “International Journal of Medical Arts” March 2009 in “Hair transplant forum international” 15 citations
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July 2021 in “AAPS PharmSciTech” October 2022 in “British Journal of Dermatology” 951 citations
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December 2013 in “Clinical epidemiology” PCOS is a common hormonal disorder in women that can be managed with lifestyle changes and various medications.
305 citations
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February 2007 in “Hormone and metabolic research” Human skin makes sexual hormones that affect hair growth, skin health, and healing; too much can cause acne and hair loss, while treatments can manage these conditions.
255 citations
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October 1985 in “The Journal of Clinical Endocrinology & Metabolism” Spironolactone treatment increases the amount of testosterone available in the body.
198 citations
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January 1998 in “Dermatology” The human sebocyte culture model has improved understanding of oily skin and acne, and how they can be treated.
169 citations
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August 2004 in “Baillière's best practice & research. Clinical obstetrics & gynaecology/Baillière's best practice and research in clinical obstetrics and gynaecology” Lower doses of treatments for hirsutism and acne in PCOS are effective and cause fewer side effects.
150 citations
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February 2008 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” Antiandrogens are somewhat effective in reducing excessive hair growth in women.
130 citations
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September 1990 in “Journal of the American Academy of Dermatology” Flutamide effectively reduced excessive hair growth and improved related symptoms in hirsutism patients without significant side effects.
121 citations
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April 2008 in “The Journal of Clinical Endocrinology & Metabolism” Insulin sensitizers may slightly reduce hirsutism but are less effective than other treatments.