research A Spontaneous Fatp4/Scl27a4 Splice Site Mutation in a New Murine Model for Congenital Ichthyosis
A gene mutation in mice causes severe skin disorder similar to a human condition.
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research Eclipta prostrata promotes the induction of anagen, sustains the anagen phase through regulation of FGF-7 and FGF-5
Eclipta prostrata helps hair growth and maintains the growth phase by affecting certain growth factors.
research A pathophysiological and clinical review of androgenetic , areata, anagen effluvium, telogen effluvium and traction alopecia’s
Understanding different types of hair loss helps in accurate diagnosis and treatment.
research Oral Spermidine Supplementation Prolongs Hair Follicle Anagen Phase with Sustained Effects: A Randomized, Double-Blind, Placebo-Controlled Trial
Spermidine supplements can help extend the hair growth phase and may be useful for treating hair loss.
research Effect of Adenovirus-Mediated Expression of Sonic Hedgehog Gene on Hair Regrowth in Mice With Chemotherapy-Induced Alopecia
Using a gene therapy with the Sonic Hedgehog gene helps mice regrow hair faster after losing it from chemotherapy.
research Mucocutaneous reactions to chemotherapy
Chemotherapy can cause various skin reactions, with hair loss being the most common, and proper diagnosis and treatment of these reactions are important.
research A Murine Model for Inducing and Manipulating Hair Follicle Regression (Catagen): Effects of Dexamethasone and Cyclosporin A
Dexamethasone speeds up hair loss in mice, while cyclosporin A slows it down.
research The Pathogenesis of Alopecia Areata in Rodent Models
Alopecia Areata is an autoimmune disease affecting hair follicles, influenced by genetic and environmental factors, with rodent models being essential for research.
research Chi-miR-30b-5p inhibits dermal papilla cells proliferation by targeting CaMKIIδ gene in cashmere goat
A specific microRNA, chi-miR-30b-5p, slows down the growth of hair-related cells by affecting the CaMKIIδ gene in cashmere goats.
research Failure to induce alopecia areata in C3H/HeJ mice with exogenous interferon gamma
Interferon gamma alone can't cause alopecia areata in C3H/HeJ mice.
research Hair Disorders
Understanding normal hair growth and loss in children is key to diagnosing and treating hair disorders.
research Influence of TRPV3 mutation on hair growth cycle in mice
The TRPV3 gene mutation affects hair growth by keeping mice in the growth phase longer, which could help treat hair loss.
research mTOR signaling promotes stem cell activation via counterbalancing BMP-mediated suppression during hair regeneration
mTOR signaling helps activate hair stem cells by balancing out the suppression caused by BMP during hair growth.
research Mutant laboratory mice with abnormalities in hair follicle morphogenesis, cycling, and/or structure: An update
The document concludes that mouse models are crucial for studying hair biology and that all mutant mice may have hair growth abnormalities that require detailed analysis to identify.
research Gata6 promotes hair follicle progenitor cell renewal by genome maintenance during proliferation
Gata6 is important for protecting hair growth cells from DNA damage and keeping normal hair growth.
research Activation of β-Catenin Signaling in CD133-Positive Dermal Papilla Cells Drives Postnatal Hair Growth
Activating β-catenin in certain skin cells speeds up hair growth in mice.
research Partial Proteasome Inhibitors Induce Hair Follicle Growth by Stabilizing β-Catenin
Certain inhibitors applied to the skin can promote hair growth by maintaining a key hair growth signal.
research Prostaglandin-Induced Hair Growth
Latanoprost can make eyelashes longer, thicker, and darker.
research A Guide to Assessing Damage Response Pathways of the Hair Follicle: Lessons From Cyclophosphamide-Induced Alopecia in Mice
The document concludes that assessing hair follicle damage due to cyclophosphamide in mice involves analyzing structural changes and suggests a scoring system for standardized evaluation.
research The genetics of hair shaft disorders
The article explains the genetic causes and symptoms of various hair disorders and highlights the need for more research to find treatments.
research Clinical and histological challenge in the differential diagnosis of diffuse alopecia: female androgenetic alopecia, telogen effluvium and alopecia areata – part I
Diagnosing hair loss disorders needs clinical, dermoscopic, and histological differences, and checking menstrual cycle, weight changes, drug therapy, and nail changes.
research Expression Level of Prostaglandin D2 Receptor 2 Regulates Hair Regression
Higher levels of the DP2 receptor may lead to hair loss.
research Hair Disorders
Different hair disorders have specific treatments and outcomes, with some resolving on their own and others requiring medication or emotional support.
research The histopathology of alopecia areata in vertical and horizontal sections
Horizontal scalp biopsy sections are better for diagnosing alopecia areata, showing fewer hair follicles and more miniaturized hairs.
research Glycogen Phosphorylase Inhibitor Promotes Hair Growth via Protecting from Oxidative-Stress and Regulating Glycogen Breakdown in Human Hair follicles
A new compound, HTPI, promotes hair growth by protecting cells from damage and regulating energy use.
research Stem cell quiescence acts as a tumour suppressor in squamous tumours
Inactive hair follicle stem cells help prevent skin cancer.
research Differential diagnosis of hair loss in children. Differentialdiagnose des Haarausfalls bei Kindern
The document concludes that early diagnosis and treatment are crucial for children with hair loss to prevent permanent damage, although not all conditions can be effectively treated.
research Exogen, Shedding Phase of the Hair Growth Cycle: Characterization of a Mouse Model
Researchers found that hair shedding happens mostly when new hair is growing and involves a unique process.
research From Telogen to Exogen: Mechanisms Underlying Formation and Subsequent Loss of the Hair Club Fiber
Hair shedding is an active process that could be targeted to treat hair loss.
research Morroniside regulates hair growth and cycle transition via activation of the Wnt/β-catenin signaling pathway
Morroniside may help hair grow and stay in its growth phase by affecting certain cell signals.