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Matriptase is crucial for skin barrier, hair growth, and may contribute to skin cancer.

A gene mutation in mice causes skin defects and early death.

The TGM3 gene's promoter region is key for skin and hair cell function and may aid gene therapy.

Ptprq has multiple forms that change during inner ear development.

Transglutaminase activity is important for skin and is found in both mammals and birds.

Different STUB1 gene mutations cause varied symptoms in autosomal recessive ataxias.

A new mRNA variant of the SCF gene in sheep skin produces a shorter, different protein.

Sostdc1 controls the size and number of hair and mammary gland structures.

Steroid sulfatase inhibitors could potentially treat hormone-related disorders like certain cancers, hair loss, acne, and improve cognitive dysfunction.

Enzyme purified and characterized for minoxidil sulphation in rat liver.

A substance called Compound 2g can strongly block STS (a hormone-related enzyme) without affecting estrogen levels, making it potentially good for treating breast cancer.

Lack of KSR1 stops certain skin tumors in mice.

Reduced matriptase activity causes skin and hair issues in both humans and mice.

The Ysc84/SH3yl1 protein family is important for cell movement and the process of taking in materials by interacting with actin and cell membranes.

S100A3 protein is crucial for hair shaft formation in mice.

TGM3 is important for skin and hair structure and may help diagnose cancer.

Human TMEM2 does not break down hyaluronan but helps control its metabolism.

ETS2 is crucial in squamous cell carcinoma development and could be a therapeutic target.

Targeting METTL1 may help slow papillary thyroid cancer growth and spread.

Overexpressing 14-3-3σ in mice skin reduces cell growth and hair density.

GLI2 increases follistatin production in human skin cells.

S100A6 protein is linked to disease progression, especially in cancers.

Researchers created a mouse with the same mutation as humans with trichothiodystrophy, showing similar symptoms and confirming the condition is due to defects in DNA repair and gene activity.

Both SMS1 and SMS2 are crucial for normal hair growth and cycle in mice.

A new genetic variant causes BRESHECK syndrome by disrupting cell growth and stress response.

TMPRSS2 helps viruses enter cells and protects the prostate from inflammation-related cancer.

Human enzymes can detoxify harmful substances but might also increase their cancer risk.

The analysis of a large pilomatricoma revealed five distinct areas with different gene activity related to hair growth and tumor development.