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A new method was created to test the effectiveness of Dihydrotestosterone (DHT) inhibitors, like finasteride and dutasteride, in human and fish cells. The results showed fish cells are more sensitive to these treatments, and dutasteride works better than finasteride in all tested cells.

New treatments for prostate cancer and BPH show promise, including novel compounds that target hormone synthesis and response.

Finasteride and dutasteride may cause depression and anxiety, especially in younger men.

High-dose dutasteride reduces PMDD symptoms by stabilizing neurosteroid levels.

Stigmasterol may help treat hair loss, but more research is needed.

SHH protein helps nerve regeneration in hypertensive rats.

Finasteride and dutasteride are equally effective and safe for treating benign prostatic hyperplasia.

Drugs targeting the Androgen Receptor are effective for treating prostate cancer and other androgen-related conditions.

Finasteride treats enlarged prostate and hair loss, but may cause side effects in some patients.

Female mice with disrupted 5α-reductase 1 had significant metabolic issues, including stress response problems, insulin resistance, liver fat buildup, and obesity.

The compounds tested could potentially treat hair loss and alopecia.

Two different mutations in the vitamin D receptor gene cause different symptoms and responses to treatment in Lebanese patients with hereditary rickets.

5α-Reductase inhibitors may increase depression risk but not dementia or suicide.

A genetic defect causes males in some Mediterranean populations to be born with ambiguous genitalia and develop male traits at puberty.

Finasteride safely lowers DHT levels without affecting testosterone.

As people age, certain enzymes in scalp glands decrease, affecting hair health.

Women with PCOS have higher 5α-reductase activity, which may be linked to insulin resistance.

New treatments for prostate cancer are less toxic and show promise, but more research is needed to enhance their effectiveness and reduce side effects.

A specific gene mutation causes vitamin D resistance, but certain vitamin D analogs might help.

Vitamin D receptor binds similarly to natural and synthetic ligands, affecting gene regulation.

Two non-steroidal antiandrogens, RU 58841 and RU 56187, form a common metabolite at different rates, which may influence their effects; RU 56187 could be used for prostate cancer treatment and RU 58841 for acne treatment.

Hair loss gene linked to prostate issues.

Neuroactive steroids affect cocaine's rewarding effects through the sigma1 receptor.

Certain drugs that block specific enzymes can help treat prostate diseases.

Medicines for enlarged prostate may raise the risk of breast growth and tenderness but not breast cancer.

5α reductase type 2 enzyme mutation and oxidative stress may increase androgenetic alopecia risk in Egyptians.

Selective Androgen Receptor Modulators (SARMs) are drugs that can control the effects of androgens in different tissues, potentially having fewer side effects and promising for treating various conditions.