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Mutations at Val-889 and Arg-752 disrupt key interactions in the androgen receptor, affecting its function.

Blocking 5α-reductase can harm memory and brain structure, and increase harmful brain changes in male mice used for Alzheimer's disease research.

The B2 genes are crucial for hair growth in rats.

PF-05314882 selectively activates androgen receptors without much effect on prostate and may help in prostate cancer treatment and hair loss prevention.

The vitamin D receptor is involved in multiple body functions beyond calcium regulation, including immune response and rapid reactions not related to gene activity.

Inhibiting testosterone 5alpha-reductase may help treat benign prostatic hyperplasia.

Non-coding RNA boosts retinoic acid production and signaling, aiding regeneration.

Smaller substituents at C-17 enhance the inhibitory activity of progesterone derivatives on 5alpha-reductase.

Finasteride may treat baldness but less effective for those with 5α-reductase deficiency.

FGF5 spliceosomes inhibit rabbit hair growth by affecting gene expression.

Finasteride, a medication, is being re-evaluated for its effects and uses.

5α-reductase is essential for male sexual development and its inhibitors have potential in treating various conditions related to hormone action.

Mutations at Val-889 and Arg-752 disrupt key interactions in androgen receptor dimerization.

The vitamin D receptor has many roles in the body beyond managing calcium, affecting the immune system, hair growth, muscles, fat, bone marrow, and cancer cells.

A new compound effectively inhibits human 5α-reductase 1.

DHT deficiency may disrupt rat epididymis function by affecting estrogen receptors.

Higher levels of miR-1199-5p may reduce the effectiveness of certain prostate treatments.

The equine epididymis mainly uses type 1 5α-reductase, and both finasteride and dutasteride can inhibit its activity.

Shorter GGC triplet repeats in the androgen receptor gene are linked to less hair loss in Han men.

Neurosteroids help control dopamine responses in the brain.

Certain genetic variations in the RAB5B gene are linked to a higher risk of polycystic ovary syndrome in Chinese Han women.

Two specific SNPs in the TRPS1 gene cause excessive hair growth by altering the protein's structure.

Neuroactive steroids affect cocaine's rewarding effects through the sigma1 receptor.

Different enzymes are active in different parts of developing mouse organs.

Certain derivatives are more effective 5α-reductase type 2 inhibitors than finasteride.

AKR1D1 controls glucocorticoid levels and receptor activity in liver cells.