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The research gives new understanding on how human steroid 5α-reductases work and how drugs like finasteride inhibit them, which could help in creating new drugs.

New mutations in the DSG4 gene cause a rare hair condition.

Noggin gene inactivation causes skeletal defects in mice, varying by genetic background.

The Foxn1(-/-) nude mouse shows disrupted and expanded skin stem cell areas due to high Lhx2 levels.

CD98hc's role in skin health decreases with age.

XEDAR triggers a specific signaling pathway in cells.

PDRN helps repair tissue and improve wound healing with a high safety profile.

Tudor-SN is important for immune cells, and polyamines can promote hair growth.

Introducing the rat OTC gene partially corrected OTC deficiency in mice.

The IRF2BP2 gene affects sheep fleece quality by influencing fiber traits.

A novel CLDN1 mutation in a 2-month-old with NISCH showed improvement with symptom management.

The CRABP I gene in cashmere goats is highly conserved but has unique features at specific amino sites.

Researchers created a mouse with the same mutation as humans with trichothiodystrophy, showing similar symptoms and confirming the condition is due to defects in DNA repair and gene activity.

The research updated the skin cell profile, finding new skin cell markers and showing fibroblasts' key role in skin health.

Personalized sonidegib dosing can effectively treat Gorlin-Goltz syndrome with fewer side effects.

SOX11 and SOX4 help skin cells act like embryonic cells to heal wounds in mice.

The MTR gene affects wool quality and production in Chinese Merino sheep.

A specific gene mutation causes vitamin D resistance, but certain vitamin D analogs might help.

Overexpression of SSAT causes hair loss and skin issues, but reducing putrescine can help.

Certain genetic variants reduce enzyme activity, contributing to non-classic congenital adrenal hyperplasia.

Only one K16 gene on chromosome 17 makes a functional keratin protein.

A new mutation in the HR gene is linked to a rare form of hair loss with limb deformities.

The enzyme 5α-reductase is important for proper blood vessel development during the fertility-related transformation of the uterus lining.

Genomic prediction can improve breeding strategies for Korean Sapsaree dogs.

A variant in the KRT31 gene causes a rare hereditary hair disorder called monilethrix.

SSO helps in skin protection and keratinization.

RORA affects hair follicle stem cells' structure and movement, potentially helping treat hair loss.

Nexin 1 may help control hair growth.

The balance between cell renewal and differentiation controls the growth of cancerous cells in mouse skin.