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research 700 Tyrosine kinase 2 inhibition rescues hair follicles from IL-12–mediated immune privilege collapse and reverses the induction of human alopecia areata in a humanized mouse model

July 2022 in “Journal of Investigative Dermatology”

Inhibiting TYK2 can restore hair growth in alopecia areata.

research Aberrant DNA methylation in inflammatory skin diseases

January 2016 in “International Journal of Dermatology and Venereology”

DNA methylation changes are linked to skin diseases with inflammation.

research Pure Hair‐Nail Ectodermal Dysplasia: Expanding the HOXC13 Genotypic Spectrum

February 2026 in “Pediatric Dermatology”

research MicroRNA-302 Increases Reprogramming Efficiency via Repression of NR2F2

123 citations , November 2012 in “Stem cells”

MicroRNA-302 helps improve the conversion of body cells into stem cells by blocking NR2F2.

research Synchronous profiling and analysis of mRNAs and ncRNAs in the dermal papilla cells from cashmere goats

17 citations , June 2019 in “BMC genomics”

Non-coding RNAs help control hair growth in cashmere goats.

research Expression of the Scube3 epidermal growth factor-related gene during early embryonic development in the mouse

17 citations , December 2006 in “Gene Expression Patterns”

Scube3 gene affects mouse embryo growth in multiple areas, but needs more research.

research Polymorphism of Exon V of prolactin gene and its association with Cashmere traits in Changthangi Pashmina goats

October 2017 in “The Indian Journal of Animal Sciences”

The prolactin gene polymorphism doesn't affect cashmere quality in these goats.

research Disruption of anthrax toxin receptor 1 in pigs leads to a rare disease phenotype and protection from senecavirus A infection

7 citations , March 2022 in “Scientific reports”

Removing anthrax toxin receptor 1 in pigs prevents Senecavirus A infection and causes a rare disease similar to GAPO syndrome.

research A Mosaic Hotspot PLCD1 Variant, Detectable in Blood‐Derived DNA, Associated With Nevus Trichilemmocysticus

March 2025 in “American Journal of Medical Genetics Part A”

A rare genetic variant linked to skin cysts was found in blood DNA, suggesting its role in cyst formation.

research Cost-effectively dissecting the genetic architecture of complex wool traits in rabbits by low-coverage sequencing

1 citations , March 2022 in “bioRxiv (Cold Spring Harbor Laboratory)”

Low-coverage sequencing is a cost-effective way to identify genes related to wool traits in rabbits.

research Faculty Opinions recommendation of Autosomal-dominant woolly hair resulting from disruption of keratin 74 (KRT74), a potential determinant of human hair texture.

May 2010 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature”

A mutation in the KRT74 gene causes woolly hair by affecting hair texture.

research Distinct mutations in human basic hair keratins 1 and 6 cause monilethrix: Implications for protein structure and clinical phenotype

January 1999 in “Journal of Investigative Dermatology”

research Fibroblast Growth Factor 21 is Differentially Expressed in Flank Skin and Regulates the Proliferation of Hair Follicle Cells in Yak

January 2025 in “SSRN Electronic Journal”

research Protein Kinase C Epsilon Signals Ultraviolet Light‐induced Cutaneous Damage and Development of Squamous Cell Carcinoma Possibly Through Induction of Specific Cytokines in a Paracrine Mechanism^¶

3 citations , January 2005 in “Photochemistry and Photobiology”

Protein kinase C epsilon may promote skin cancer development after UV exposure by affecting nearby cells.

ROBO4 Deletion Ameliorates PAF-Mediated Skin Inflammation by Regulating the mRNA Translation Efficiency of LPCAT1/LPCAT2 and the Expression of PAF Receptor

research ROBO4 deletion ameliorates PAF-mediated skin inflammation via regulating the mRNA translation efficiency of LPCAT1/LPCAT2 and the expression of PAF receptor

6 citations , January 2020 in “International journal of biological sciences”

Removing the ROBO4 gene in mice reduces skin inflammation and hair loss by affecting certain inflammation pathways and gene expression.

research Autosomal recessive pure hair and nail ectodermal dysplasia linked to chromosome 12p11.1-q14.3 without KRTHB5 gene mutation

11 citations , July 2010 in “European Journal of Dermatology”

The condition is linked to chromosome 12, but no mutations were found in the known genes.

research JAK-centric explainable few-shot gene-expression diagnosis framework for alopecia via MultiPLIER priors and relation-style set-to-set comparison

January 2026 in “Frontiers in Molecular Biosciences”

A new method helps diagnose alopecia areata using specific gene markers and could guide targeted treatments.

research Dermal EZH2 orchestrates dermal differentiation and epidermal proliferation during murine skin development

6 citations , June 2021 in “Developmental biology”

Dermal EZH2 controls skin cell development and hair growth in mice.

research Keratin 71 Mutations: From Water Dogs to Woolly Hair

11 citations , September 2012 in “The journal of investigative dermatology/Journal of investigative dermatology”

A mutation in the KRT71 gene causes a hair disorder by disrupting hair follicle structure and texture.

research Identification of genes and proteins associated with anagen wool growth

10 citations , September 2016 in “Animal genetics”

Researchers identified key genes and proteins linked to wool growth in sheep.

research 606 Connecting signaling dynamics with cell fates in live mice

April 2021 in “Journal of Investigative Dermatology”

Stem cells control their future role by changing ERK signal timing, affecting tissue regeneration and cancer.

Expression Patterns of Three Estrogen Receptor Genes During Zebrafish Development: Evidence for High Expression in Neuromasts

research Expression patterns of three estrogen receptor genes during zebrafish (Danio rerio) development: evidence for high expression in neuromasts

77 citations , April 2004 in “Gene expression patterns”

The three estrogen receptor genes are highly expressed in zebrafish neuromasts during development.

research Exome-wide age-of-onset analysis reveals exonic variants in ERN1 and SPPL2C associated with Alzheimer’s disease

12 citations , February 2021 in “Translational Psychiatry”

Researchers found two new genetic variants linked to Alzheimer's disease.

research Long non-coding RNA Xist contribution in systemic lupus erythematosus and rheumatoid arthritis

41 citations , January 2022 in “Clinical Immunology”

Females are more prone to lupus and arthritis due to X chromosome factors.

N6-Methyladenosine Modification of circRNA-ZNF638 Contributes to the Induced Activation of SHF Stem Cells Through miR-361-5p/Wnt5a Axis in Cashmere Goats

research N6-Methyladenosine modification (m6A) of circRNA-ZNF638 contributes to the induced activation of SHF stem cells through miR-361-5p/Wnt5a axis in cashmere goats

2 citations , November 2022 in “Animal Bioscience”

A specific RNA modification in cashmere goats helps activate hair growth-related stem cells.

research 26-SNP Panel Aids Guiding Androgenetic Alopecia Therapy and Provides Insight into Mechanisms of Action

September 2025 in “Cosmetics”

Genetic profiling can improve androgenetic alopecia treatment by predicting drug response and minimizing side effects.

research Identification of a Novel Missense Mutation in the Fibroblast Growth Factor 5 Gene Associated with Longhair in the Maine Coon Cat

2 citations , June 2021 in “Research Square (Research Square)”

A new gene mutation causes long hair in some Maine Coon cats.

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