research The effect of spironolactone on genital skin 5α-reductase activity
Spironolactone reduces the enzyme activity that converts testosterone to DHT, helping treat excessive hair growth in women.
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research 891 Comparison of phenotypes and transcriptomes of mouse skin-derived precursors and dermal mesenchymal stem cells
The search scheme SMRI is faster and more secure for retrieving encrypted data from the cloud.
research Sex Hormones: Hormonal Contraception and Hormone Replacement Therapy
Hormonal contraceptives and therapies regulate organ functions and treat various conditions.
research Common dermatological complaints and their psychosocial impact: a descriptive cross-sectional study among undergraduates of an outstation university of Sri Lanka.
Many students at Rajarata University in Sri Lanka experience skin issues like acne, causing significant stress and concern.
research Post-finasteride syndrome: survey of dermatologists from the Spanish Hair and Nail Disorders Group
Most dermatologists think post-finasteride syndrome is rare, possibly psychiatric, and needs more research.
research Glia-derived steroids modulate epileptogenesis in a model of temporal lobe epilepsy
Neurosteroids from glia cells help control seizure development in epilepsy.
research Syndromes of Severe Insulin Resistance (SSIRs)
The document concludes that Syndromes of Severe Insulin Resistance are rare disorders with limited treatment options.
research 5α-Reduced glucocorticoids: a story of natural selection
Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.
research Mining and analysis of adverse event signals of isotretinoin based on the real-world data of FAERS database
Isotretinoin has many serious side effects, including some new ones, needing better safety measures and updated labels.
research Abordagens psicológicas e novas terapêuticas perante as escolhas do paciente portador da Síndrome de Morris
Patients with Complete Androgen Insensitivity Syndrome need psychological support and multidisciplinary care for complex treatment decisions.
research Finasteride
Finasteride caused serious side effects and led to six suicides.
research A SIBO-mediated aetiology for a subset of Post-Finasteride Syndrome cases: investigating gut-derived toxins
Gut bacteria overgrowth may cause some Post-Finasteride Syndrome symptoms.
research Inhibition of 5α-reductase in the nucleus accumbens counters sensorimotor gating deficits induced by dopaminergic activation
Finasteride may help improve certain brain function issues linked to dopamine.
research Dipyridamole-Associated Shock and Pulmonary Edema; Oxcarbazepine-Induced Resistant Ventricular Fibrillation; Finasteride-Induced Pseudoporphyria; Suicidal Ideation Associated with Asenapine; Rediscovering Adverse Anticholinergic Effects; Prevalence of Adverse Drug Events in Ambulatory Care
research RETRACTED ARTICLE: Interaction Study Between Finasteride and Tamsulosin in Healthy Young Male Subjects
research The 5α-Recluctase System and Its Inhibitors
5 alpha-reductase inhibitors, like finasteride, are used to treat conditions like prostate issues and skin disorders.
research Beyond Clinical Efficacy: A Literature Review on the Safety Challenges of Isotretinoin Therapy
Isotretinoin can safely and effectively control acne with proper risk management and monitoring.
research Effect of Neurosteroid Withdrawal on Hippocampal GABA‐A Receptor α4‐Subunit Expression in Female Mice
Neurosteroid withdrawal increases α4 subunit expression in the hippocampus, which may relate to catamenial epilepsy in women.
research Facial contact dermatitis due to spironolactone in an anti‐acne cream
Spironolactone in anti-acne cream can cause allergic skin reactions in some people.
research Testosterone, 17 Ks, 17 beta E2 FSH-LH variations and hirsutism modifications during spironolactone therapy.
Spironolactone treatment reduced hair growth and androgen levels in hirsute women, but the overall effectiveness was just adequate.
research [Two drugs have a better outcome. Finasteride plus alpha blocker improves urine flow].
research Post-Finasteride Syndrome: An Underestimated Phenomenon
Finasteride and dutasteride, used for prostate issues and hair loss, can cause side effects like sexual dysfunction and mental issues, which may continue even after stopping the medication, a condition called post-finasteride syndrome, for which there's currently no cure.
research 1370 MTORC1 activity is increased in the skin of acne patients and is suppressed with isotretinoin treatment
Acne patients have higher skin mTORC1 activity, which is reduced by isotretinoin treatment.
research TREATMENT OF ACNE VULGARIS, OR EVERYTHING WE SHOULD KNOW ABOUT ISOTRETINOIN
Isotretinoin effectively treats severe acne but has significant side effects requiring careful monitoring.
research Predictive factors for therapeutic response and cluster analysis in syndrome of undifferentiated recurrent fever (SURF)
IL-1 blockade is effective for treating SURF, and personalized treatment is needed.
research Finasteride
research Contraceptive use in acne
Hormonal contraceptives can help treat acne by affecting sebum production and androgen levels.
research 5α-Reductase inhibitors alter steroid metabolism and may contribute to insulin resistance, diabetes, metabolic syndrome and vascular disease: a medical hypothesis
Some hair loss and prostate drugs might increase the risk of diabetes and heart disease.
research A New Look at the 5á-Reductase Inhibitor Finasteride
Finasteride, a medication, is being re-evaluated for its effects and uses.
research [Combined treatment of BPS with tamsulosin and finasteride : Literature review and prescription data].
Using tamsulosin and finasteride together for benign prostatic syndrome has increased and shows improvement in symptoms, but more reliable comparisons are needed.