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The review suggests younger men taking 1 mg finasteride report more side effects, including sexual, skin, metabolic, and psychological issues.

S-equol supplements significantly reduced menopausal symptoms in most women.

Mirtazapine can cause male breast enlargement.

All three treatments reduce hirsutism, but spironolactone works best long-term.

The conclusion is that doctors should be careful when prescribing 5α-reductase inhibitors due to possible serious side effects, and they should discuss these risks with patients.

5α-reductase inhibitors increase the risk of sexual dysfunction, especially in men with enlarged prostate.

Finasteride for hair loss often causes depression, with risks outweighing benefits.

Finasteride is not proven to cause depression or suicide, and careful patient monitoring is advised.

Finasteride may cause lasting sexual and mental health issues, and genetic screening could help prevent them.

Combination drug therapy is effective for hirsutism that doesn't improve with just one medication.

The treatment improved acne, seborrhoea, and hirsutism, with some side effects like spotting and nervousness.

The document concludes that the risk of sexual side effects from 5-alpha-reductase inhibitors is low and often temporary, but more research is needed on potential permanent effects.

Spironolactone effectively reduces symptoms of hyperandrogenism but has some side effects.

HDAC inhibitors help brain cells grow and improve brain function.

Probiotics may help improve depression in women with PCOS.

A patient with Satoyoshi syndrome improved with a treatment combining several medications, including carbamazepine and methotrexate.

Finasteride may cause depression and affect brain and gut health in male rats.

A cystic fibrosis patient developed Cushing's syndrome from a drug interaction between itraconazole and budesonide, which improved after stopping the medications.

Neuroactive steroids affect cocaine's rewarding effects through the sigma1 receptor.

Long-term Finasteride treatment reduces depression better than short-term treatment in rats.

Cyproterone acetate and ethinylestradiol effectively reduce hirsutism and acne in women.

Finasteride can cause side effects, some lasting after treatment ends, and may lead to severe depression or suicidal thoughts.

Prenatal stress changes how male and female rats enjoy rewards differently, linked to sex hormones.

A teenage girl's excessive hair growth was caused by a medication for mania, but improved after stopping the medication.

The effectiveness of statins for women with PCOS is unclear.