March 2026 in “Actas Dermo-Sifiliográficas” Most dermatologists think post-finasteride syndrome is rare, possibly psychiatric, and needs more research.
February 2026 in “Zenodo (CERN European Organization for Nuclear Research)” Gut bacteria overgrowth may cause some Post-Finasteride Syndrome symptoms.
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July 2013 in “The Journal of Sexual Medicine” Finasteride use changes brain chemicals, causing lasting sexual issues and anxiety/depression.
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November 1984 in “JAMA” Certain medications, like trimethoprim, can cause aseptic meningitis, especially in people with autoimmune conditions.
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September 2020 in “Clinical endocrinology” Some antiandrogens may lower testosterone better than others, but it's unclear which is best for feminization in transgender women; more research is needed.
January 2011 in “Reactions Weekly” St. John's Wort may reduce the effectiveness of finasteride by increasing its breakdown in the body.
April 2024 in “Journal of psychiatric research” Short-term finasteride use in male rats caused anxiety, depression, and memory problems.
Finasteride may help reduce COVID-19 infection by altering a key gene.
May 2011 in “Value in Health” CP-690,550 significantly reduced itching in patients with moderate-to-severe plaque psoriasis.
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February 1999 in “PubMed” Finasteride, a drug, can block the seizure-preventing effects of a hormone called progesterone in mice.
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September 2003 in “Journal of Medicinal Chemistry” A substance called Compound 2g can strongly block STS (a hormone-related enzyme) without affecting estrogen levels, making it potentially good for treating breast cancer.
April 2026 in “Brain Sciences” Finasteride may cause depression and suicidal thoughts, especially in young men.
August 2024 in “Journal of Personalized Medicine” Tamsulosin increases the risk of floppy iris during eye surgery.
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September 2014 in “Current Opinion in Endocrinology, Diabetes and Obesity” Finasteride and dutasteride effectively treat hair loss in men and women, but may cause side effects like low libido and depression.
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February 2026 in “Zenodo (CERN European Organization for Nuclear Research)” Gut bacteria overgrowth may cause some Post-Finasteride Syndrome symptoms.
July 2016 in “Reactions Weekly” Cyproterone and finasteride reduced hypersexuality but caused serious side effects.
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November 2004 in “Endocrinology” SARMs may offer benefits by boosting muscle effects without unwanted side effects.
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January 2004 in “Neuroscience” Testosterone increases seizure risk through its conversion to specific neurosteroids.
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October 2010 in “BJUI” 5-α-reductase inhibitors reduce prostate cancer risk but may cause sexual dysfunction and don't affect high-grade tumor or death rates.
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April 2015 in “Behavioural Brain Research” Finasteride worsens stress effects on sensory processes, possibly linking to anxiety/depression.
May 2024 in “Psychiatric News” Weight-loss drugs are not linked to suicidal thoughts.
Neurosteroids help control dopamine responses in the brain.
January 2022 in “Essentials in ophthalmology” Tamsulosin increases the risk of floppy iris syndrome during cataract surgery.
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November 1991 in “American Journal of Psychiatry” Fluoxetine was not effective in treating hair-pulling disorder in the short term.