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LGR5 is a common marker of hair follicle stem cells in different animals and is important for hair growth and regeneration.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Increasing SSAT makes skin more prone to cancer.

GATA6 is important for maintaining and differentiating cells in a key area of human skin.

A small change in the TRPS1 gene leads to a less severe form of a syndrome affecting hair, nose, and finger development.

Introducing the rat OTC gene partially corrected OTC deficiency in mice.

TP0427736 may help treat hair loss by blocking a specific protein and promoting hair growth.

LGR5 helps maintain corneal cell characteristics and prevents unwanted changes by controlling specific cell signaling pathways.

BSSP may help skin tumors grow and could be a marker or target for skin cancer treatment.

The treatments stopped hair regrowth in mice.

Finasteride, a medication, is being re-evaluated for its effects and uses.

Baricitinib was effective in treating a patient with dermatomyositis and hair loss.

Androgens regulate 5 alpha-reductase activity in hamster sebaceous glands.

Newly designed proteins can effectively degrade specific proteins in cells, offering a promising alternative for targeted protein degradation.

SRD5A1 is crucial in advanced prostate cancer, and blocking both SRD5A1 and SRD5A2 is more effective than targeting SRD5A2 alone.

LGR5 and LGR6 are expressed differently in various skin tumors, which may offer clues about their origins.

Blocking a protein called CXXC5 with a specific peptide can stimulate hair regrowth and new hair growth in wounds.

A genetic mutation in the hHa1 gene creates a smaller, but still functional, hair protein without causing hair problems.

Mutations in the SRD5A3 gene cause a new type of glycosylation disorder by blocking the production of a molecule necessary for protein glycosylation.

A cat's poor wound healing was linked to a genetic deletion in the COL5A1 gene.

ALKBH5 helps wounds heal faster by stabilizing PELI2 mRNA.

The STIM1 R304W mutation in mice leads to bone changes and teeth hair growth.

A new method was developed to accurately measure enzyme activity related to prostate health.

WNT10B is linked to cancer development and affects survival and disease progression in various cancers.

A new mutation in the ST14 gene broadens the understanding of ichthyosis-hypotrichosis syndrome.

PRO-C22 can help diagnose and monitor the severity of hidradenitis suppurativa.