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A specific metabolite, not a receptor protein, triggers the production of certain kidney enzymes, but this process is disrupted in mice with a mutation causing testicular feminization.

The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.

The S1PR 1&4 modulator may effectively treat alopecia areata by reducing hair loss and immune cell activity.

Compound 7b is a promising candidate for treating benign prostatic hyperplasia and prostate cancer.

Lack of cystatin M/E causes thin hair and dry skin.

Dermatologists need more training on isotretinoin's eye side effects.

Inducing ferroptosis in hepatic stellate cells is crucial for treating liver fibrosis.

Prostaglandin D2 increases testosterone production in skin cells through a process involving reactive oxygen species, and antioxidants may help treat hair loss.

DHEA reduction may be linked to frontal fibrosing alopecia, but more research is needed.

A specific gene variant is linked to heart disease, increased heart muscle, curly hair, and thick skin on palms and soles.

A mother's western diet can make her milk toxic, causing inflammation and hair loss in babies.

The guidelines suggest lifestyle changes, diet adjustments, and personalized medication to manage dyslipidemia and reduce heart disease risk.

Keeping human skin stem cells is easier with low temperatures and mTOR inhibition.

COX-2 levels change during the hair cycle and affect skin and hair growth.

Glucocorticoids and thyroid hormones together are essential for fetal fat development.

Reducing Tyrosinase prevents mature color pigment cells from forming in mouse hair.

The compounds tested could potentially treat hair loss and alopecia.

The study found that in Eclipta prostrata roots, coumestans come from acetate and shikimate pathways, and phenylpropanoid is made only through the shikimate pathway.

The enzyme 5α-reductase is key in causing psychotic-like effects from sleep deprivation.

Targeting the protein Caveolin-1 might help treat a type of scarring hair loss called Frontal Fibrosing Alopecia.

Coconut oil boosts testosterone but doesn't fully trigger reproductive maturity in pufferfish.

Adapalene 0.1% effectively reduces acne by decreasing comedones and altering skin properties.

Targeting impaired Nrf2 signaling might help treat hidradenitis suppurativa early on.

Double-stranded RNA helps regenerate hair follicles by increasing retinoic acid production and signaling.

Metabolism plays a key role in determining stem cell fate.

A small change in the TRPS1 gene leads to a less severe form of a syndrome affecting hair, nose, and finger development.

Oral retinoids are effective for treating severe skin disorders but have reversible side effects and risks for pregnant women.

A reliable model for screening type II 5α-reductase inhibitors was created and validated.

C-reactive protein helps monocytes stick to blood vessel cells by causing oxidative stress.