298 citations
,
January 2014 in “BioMed Research International” Stem cell-derived conditioned medium shows promise for treating various medical conditions but requires standardized production and further validation.
144 citations
,
June 2008 in “Cell Cycle” Hair follicle stem cells can help repair spinal cord injuries and improve walking.
48 citations
,
February 2016 in “Scientific Reports” Researchers created rat liver stem cells that could help repair liver failure in rats and may be useful for studying human liver diseases.
15 citations
,
September 2007 in “Cell & tissue research/Cell and tissue research” Embryonic and adult stem cells are valuable for improving skin grafts and cell therapy.
4 citations
,
May 2015 in “Macedonian Veterinary Review” Canine stem cell aggregates can effectively replace natural dermal papillae for hair research.
4 citations
,
January 2011 in “Cell stem cell” Hair follicle stem cells can return to their original niche and help regenerate hair.
3 citations
,
October 2020 in “Journal of Investigative Dermatology” Removing β-catenin in certain stem cells causes hair whitening and pigmentation issues.
3 citations
,
January 2021 in “OALib” Mesenchymal stem-cell derived extracellular vesicles show promise in plastic surgery but need more research for safe use.
3 citations
,
December 2007 in “Journal of Otology” Guinea pig fat stem cells can become hair cell-like cells in a lab.
2 citations
,
March 2021 in “Andrologia” Stem cell therapy affects 15 key genes in rats with diabetes-related erectile dysfunction.
April 2026 in “Journal of Cosmetic Dermatology” Exosomes from umbilical cord stem cells help protect hair color and health under stress.
August 2025 in “Stem Cell Research & Therapy” Exosomes from stem cells can help regrow hair better than minoxidil.
238 citations
,
April 2012 in “Cell stem cell” Targeting and modifying the stem cell niche can improve regenerative therapies.
43 citations
,
July 2019 in “Stem Cells International” Advancements in creating skin grafts with biomaterials and stem cells are promising, but more research is needed for clinical application.
14 citations
,
March 2022 in “Journal of Biomedical Science” Cyanidin 3-O-arabinoside may help treat a common form of hair loss by protecting cells against aging and improving cell function.
13 citations
,
December 2014 in “Stem Cells” Hair and skin can regenerate without bulge stem cells due to other compensating cells.
2 citations
,
May 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” Stem cells help remove dead cells to keep tissues healthy by balancing cell replacement and clearance.
April 2024 in “Cell death and differentiation” Cell death shapes skin stem cell environments, affecting inflammation, repair, and cancer.
November 2023 in “Journal of Investigative Dermatology” Adipose stem cell exosomes may effectively treat atopic dermatitis by reducing inflammation and improving skin health.
September 2023 in “Frontiers in cell and developmental biology” Vav2 changes how hair follicle stem cells' genes work as they age, which might improve regeneration but also raise cancer risk.
January 2017 in “PRISM (University of Calgary)” Unique genes in hair follicle cells help tissue regeneration.
June 2024 in “Regenerative Therapy” iPSCs show promise for hair regeneration but need more research to improve reliability and effectiveness.
95 citations
,
October 2020 in “Cell & Bioscience” Mesenchymal stem cell therapy shows promise for liver disease but faces challenges in standardization and approval.
32 citations
,
May 2020 in “European Journal of Pharmacology” Stem cell therapies show promise for hair regrowth but face production and application challenges.
26 citations
,
September 2012 in “Cell Reports” B-Raf and C-Raf are essential for maintaining melanocyte stem cells to prevent hair graying.
10 citations
,
May 2020 in “Frontiers in cell and developmental biology” MicroRNAs are important for hair growth regulation, with Dicer being crucial and Tarbp2 less significant.
January 2019 in “Elsevier eBooks” Understanding stem cell environments is key to developing treatments for various diseases and injuries.
May 2020 in “Research Square (Research Square)” Human stem cells can turn into functional eye cells that might help treat retinal diseases.
52 citations
,
February 2012 in “PloS one” Lack of Ctip2 in skin cells delays wound healing and disrupts hair follicle stem cell markers in mice.
30 citations
,
August 2021 in “Oncogene” miR-22 helps skin cancer grow and spread by activating specific cell signals.