research Precision therapeutics in non-scarring alopecia: a systemic genomic and pathway-based framework for targeted interventions
Personalized treatments for hair loss focus on specific genetic and biological pathways.
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research Medical Treatment for Androgenetic Alopecia
New treatments for common hair loss include medications, regenerative therapies, and laser therapy, but may not work for everyone.
research Generation of iPS-derived model cells for the analysis of hair development
Researchers created a cell model to study hair growth and test hair-growth drugs.
research Induced pluripotent stem cells: Generation methods and a new perspective in COVID-19 research
iPSCs are promising for studying and treating COVID-19.
research Generation of iPS-derived model cells for analyses of hair shaft differentiation
Researchers created a mouse cell line to study hair growth and test hair growth drugs.
research Hair Follicle Development in Mouse Pluripotent Stem Cell-Derived Skin Organoids
Scientists grew hair follicles from mouse stem cells in a lab setting.
research Defining the hair follicle stem cell (Part I)
Hair follicle stem cells are key for hair growth and skin repair.
research Differential expression levels of Sox9 in early neocortical radial glial cells regulate the decision between stem cell maintenance and differentiation
Sox9 levels in brain stem cells affect whether they stay as stem cells or become neurons.
research Microfluidic Technology for the Generation of Cell Spheroids and Their Applications
Microfluidic technology improves cell spheroid creation for better drug testing and tissue engineering.
research The TRF1 telomere protein is essential for the generation and maintenance of iPS cells and marks both pluripotent and adult stem cells
TRF1 is crucial for creating and maintaining stem cells and marks both pluripotent and adult stem cells.
research Generating hair follicle inductive dermal papillae cells from adipose derived mesenchymal stem cells
Adipose-derived stem cells can be used to create cells that help grow new hair.
research 1386 Estetrol prolongs anagen in healthy female scalp hair follicles by positively modulating dermal papilla functions and generation of progenitor stem cells ex vivo
Estetrol may help prevent hair loss and promote hair growth in women.
research Generation of Induced Pluripotent Stem Cells from Hair Follicle Bulge Neural Crest Stem Cells
Hair follicle stem cells need all reprogramming factors to become pluripotent.
research Uncomplicated differentiation of stem cells into bipolar neurons and myelinating glia
Hair follicles can be used to easily create neurons and glial cells for potential nerve repair.
research Use of Induced Pluripotent Stem Cells in Dermatological Research
iPSCs can help treat genetic skin disorders by creating healthy skin cells from a small biopsy.
research Faculty Opinions recommendation of GDNF promotes hair formation and cutaneous wound healing by targeting bulge stem cells.
GDNF helps grow hair and heal skin wounds by acting on specific stem cells.
research Watching stem cells at work with a flexible multiphoton tomograph
A new imaging technique can observe stem cells in living mice without harming them.
research Exploring the Differentiation Abilities of Hair Follicle and Dental Pulp Stem Cells Into Islet Like Cells
Hair follicle stem cells are better than dental pulp stem cells at becoming insulin-producing cells, useful for diabetes therapy.
research Regulation of somatic cell reprogramming through inducible mir-302 expression
Increasing mir-302 turns human hair cells into stem cells by changing gene regulation and demethylation.
research Next generation human skin constructs as advanced tools for drug development
Advanced human skin models improve drug development and could replace animal testing.
research Long-term time-lapse multimodal intravital imaging of regeneration and bone-marrow-derived cell dynamics in skin
The study introduced a new imaging technology to track skin healing and bone marrow cell activity over time.
research Isolating subpopulations of human epidermal basal cells based on polyclonal serum against trypsin-resistant CSPG4 epitopes
The research found a way to identify and study skin cells with stem cell traits, revealing they behave differently in culture and questioning current stemness assessment methods.
research Hair care, Therapies and Transplantation
Different types of hair loss can be caused by hormones, stress, autoimmune disorders, illness, or nutritional deficiencies, and can be treated with medication, nutritional supplements, or hair transplantation.
research A novel and safe small molecule enhances hair follicle regeneration by facilitating metabolic reprogramming
Small molecule IM boosts hair growth by changing stem cell metabolism.
research Organ regeneration based on developmental biology: past and future
Scientists have made progress in growing mini-organs and regenerating parts of the skin, with plans to treat hair loss in a future trial.
research Therapeutic strategies for treating hair loss
The conclusion is that we need more effective hair loss treatments than the current ones, and these could include new drugs, gene and stem cell therapy, hormones, and scalp cooling, but they all need thorough safety testing.
research Self-assembled complete hair follicle organoids by coculture of neonatal mouse epidermal cells and dermal cells in Matrigel
Scientists created complete hair-like structures by growing mouse skin cells together in a special gel.
research UT-018 Accelerates Wound Repair and Hair Follicle Regeneration in Murine Models
UT-018 speeds up wound healing and boosts hair growth in mice.
research Mechanical Instability of Adherens Junctions Overrides Intrinsic Quiescence of Hair Follicle Stem Cells
Weak cell junctions disrupt hair follicle stem cell rest.
research Hair follicle organoids: advances in construction, applications, and translational challenges
Hair follicle organoids can help study hair biology and disorders but need improvements for wider use.