October 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” A protein called EGFR protects hair follicle stem cells, and when it's disrupted, hair follicles can be damaged, but blocking certain pathways can restore hair growth.
April 2017 in “Journal of Investigative Dermatology”
37 citations
,
April 2017 in “npj Regenerative Medicine” PDGF signaling is crucial for maintaining and renewing hair follicle stem cells, which could help treat hair loss.
64 citations
,
January 2009 in “The International journal of developmental biology” Hair follicle stem cells are controlled by their surrounding environment.
4 citations
,
November 2021 in “Frontiers in Cell and Developmental Biology” Aging causes hair loss and graying due to stem cell decline and changes in cell behavior and communication.
July 2025 in “World Journal of Stem Cells” Stem cell-derived exosomes could be a promising new treatment for hair regrowth.
April 2024 in “Communications biology” Enzymes involved in Vitamin A metabolism affect hair growth and type in mice.
October 2021 in “QJM: An International Journal of Medicine” ADSC injections improve hair density, thickness, and reduce inflammation in female pattern hair loss.
1 citations
,
January 2016 in “Journal of stem cell research and medicine” Fat-derived stem cell therapies can potentially increase hair growth and thickness in people with hair loss.
1 citations
,
January 2016 in “Journal of stem cell research and medicine” Fat-derived stem cell therapies can potentially increase hair growth and thickness in people with hair loss.
83 citations
,
March 2015 in “International Journal of Dermatology” ADSC-CM treatment improved hair density and thickness in women with hair loss, safely and effectively.
61 citations
,
July 2011 in “PLOS ONE” Spermidine may help reduce hair loss and deserves further testing as a treatment.
38 citations
,
June 2017 in “The Journal of Dermatology” Aging in hair follicle stem cells leads to hair graying, thinning, and loss.
18 citations
,
December 2018 in “Expert Opinion on Biological Therapy” Hair follicle stem cells are promising for wound healing but require more research for safe clinical use.
113 citations
,
November 2017 in “Scientific Reports” Tiny particles from stem cells help activate hair growth cells and encourage hair growth in mice without being toxic.
101 citations
,
March 2019 in “Cell Stem Cell” Certain immune cells in the skin release a protein that stops hair growth by keeping hair stem cells inactive.
August 2023 in “Stem Cell Research & Therapy” Using adipose-derived stem cell media with minoxidil may help regrow hair in men with hair loss.
10 citations
,
January 2019 in “in Vivo” Finasteride boosts stem cell signals for hair growth.
8 citations
,
October 2020 in “Stem cell research & therapy” DNMT1 helps turn hair follicle stem cells into fat cells by blocking a specific microRNA.
6 citations
,
July 2013 in “Molecular Imaging” The technique allowed noninvasive tracking of hair stem cell survival and growth, showing potential for hair loss research.
3 citations
,
April 2022 in “Veterinary world/Veterinary World” The mesenchymal stem cell-conditioned medium gel improved burn healing and hair growth in rats better than other treatments.
December 2024 in “Research Square (Research Square)” Placental stem cell exosome therapy improves hair growth and reduces hair loss.
September 2023 in “Stem Cells International” Substances from fat-derived stem cells can promote hair growth and counteract hormone-related hair loss by activating a key hair growth pathway.
September 2016 in “Springer eBooks” Fat-derived stem cells may help treat skin aging and hair loss.
80 citations
,
September 2007 in “Cell Cycle” Stem cells in hair follicles can become various cell types, including neurons.
55 citations
,
April 2015 in “BMC medicine” Stem Cell Educator therapy helps regrow hair and improve life quality in alopecia areata patients.
29 citations
,
December 2005 in “BioEssays” Wnt/ß-catenin signaling is crucial for regulating skin stem cells and hair growth, with the right levels and timing needed for proper function.
17 citations
,
May 2021 in “Journal of Cell Science” N1-acetylspermidine promotes hair follicle stem cell self-renewal.
13 citations
,
January 2022 in “Stem cell reviews and reports” Mouse stem cells from hair follicles can improve wound healing and reduce scarring.
4 citations
,
June 2021 in “Basic and Clinical Neuroscience Journal” Rat hair follicle stem cells can improve nerve repair and muscle function after injury.