179 citations
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July 2016 in “Nature Reviews Molecular Cell Biology” Epigenetic changes control how adult stem cells work and can lead to diseases like cancer if they go wrong.
176 citations
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September 2006 in “Stem Cells” BMP signaling prevents hair growth by stopping stem cell activation.
116 citations
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September 2020 in “Nature Communications” The research identified various cell types in mouse and human teeth, which could help in developing dental regenerative treatments.
88 citations
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January 2019 in “Journal of Tissue Engineering and Regenerative Medicine” Conditioned media from mesenchymal stem cell cultures could be a more effective alternative for regenerative therapies, but more research is needed.
71 citations
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October 2017 in “Journal of Investigative Dermatology” PPAR-γ agonists like pioglitazone may help manage lichen planopilaris but don't fully reverse scarring.
71 citations
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January 2015 in “Journal of molecular cell biology/Journal of Molecular Cell Biology” mTOR signaling helps activate hair stem cells by balancing out the suppression caused by BMP during hair growth.
64 citations
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January 2013 in “The journal of investigative dermatology/Journal of investigative dermatology” Human stem cells can help form hair follicles in mice.
41 citations
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April 2019 in “PLOS genetics” CD34+ and CD34- melanocyte stem cells have different regenerative abilities.
34 citations
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April 2018 in “EMBO journal” The protein SLC1A3 is important for activating skin stem cells and is necessary for normal hair and skin growth in mice.
33 citations
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April 2020 in “Journal of Clinical Investigation” Stress in hair follicle stem cells causes inflammation in a chronic skin condition through a specific immune response pathway.
30 citations
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August 2021 in “Oncogene” miR-22 helps skin cancer grow and spread by activating specific cell signals.
28 citations
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January 2023 in “Cell Transplantation” Nanofat with stem cells is promising for treating hair loss, scars, and skin rejuvenation.
24 citations
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November 2016 in “Cell death and disease” Skin-derived stem cells can become various cell types, including germ cell-like and oocyte-like cells.
24 citations
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June 2015 in “Journal of Investigative Dermatology” aPKCλ is crucial for keeping hair follicle stem cells inactive and maintaining normal hair growth.
20 citations
,
March 2014 in “PubMed” Hair follicle stem cell research has advanced in understanding and using these cells for hair growth and skin repair.
16 citations
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January 2007 in “Dermatology” Scientists have made progress in understanding hair follicle stem cells, identifying specific genes and markers, and suggesting their use in treating hair and skin conditions.
15 citations
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January 2021 in “Journal of Materials Chemistry B” Silk nanofiber hydrogels help stem cells heal wounds faster and improve skin regeneration.
13 citations
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February 2023 in “Aging” A substance from hair follicle stem cells helps heal skin wounds in diabetic mice by promoting cell growth and preventing cell death.
13 citations
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September 2014 in “Birth defects research” Human epidermal neural crest stem cells could be used for therapies, drug discovery, and disease modeling.
11 citations
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September 2019 in “The journal of investigative dermatology/Journal of investigative dermatology” A specific group of skin stem cells was found to help maintain hair follicle cells.
9 citations
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November 2021 in “Frontiers in Cell and Developmental Biology” PBX1 helps reduce aging and cell death in hair follicle stem cells by decreasing DNA damage, not by improving DNA repair.
7 citations
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September 2020 in “Frontiers in Cell and Developmental Biology” IL-36α helps grow new hair follicles and speeds up wound healing.
6 citations
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April 2022 in “Journal of diabetes research” Type 2 diabetes slows down skin and hair renewal by blocking important stem cell activation in mice.
6 citations
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January 2022 in “BIO-PROTOCOL” The protocol allows easy imaging of dividing cells in C. elegans and can be used for other organisms.
5 citations
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November 2021 in “Plastic and Reconstructive Surgery” Using special stem cells, we can create new hair follicles, potentially making hair restoration easier and more affordable.
4 citations
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January 2012 in “Medical Hypotheses” Finasteride may improve stem cell therapy for heart attacks by increasing cell survival.
3 citations
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November 2022 in “International journal of molecular sciences” Bio-pulsed stimulation increases production of beneficial vesicles from bird stem cells that improve skin and hair cell functions.
3 citations
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April 2011 in “Expert Review of Dermatology” Male hair loss is caused by inactive hair follicle stem cells.
3 citations
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May 2008 in “Journal of Visualized Experiments” Mouse Epidermal Neural Crest Stem Cells can become various cell types.
2 citations
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September 2022 in “Organoid” A new method was developed to efficiently grow skin hair follicles from stem cells, potentially aiding alopecia treatment.