The revised study on how inflammation affects cancer stem cells was accepted after improving clarity and structure.
The revised manuscript on how inflammation affects cancer stem cells was accepted after addressing issues with clarity and detail.
The reviewers suggest major revisions for clarity and inclusion of recent findings on inflammation's role in cancer.
Reviewers suggest clarifying the abstract, adding background on inflammation's effect on cancer, discussing immune cell roles, including counter studies, and correcting grammar.
The reviewers found the manuscript on inflammation's role in cancer stem cells to be relevant but suggested it needs clarity, more background information, discussion on immune cells' role in tumors, updated references, and grammar corrections.
13 citations
,
February 2024 in “Clinical Epigenetics” Epigenetic factors affect the success of using iPSC-derived cells for spinal cord injury treatment.
March 2022 in “Authorea (Authorea)” Chemotherapy for leukemia led to full hair regrowth in a child with alopecia totalis.
31 citations
,
April 2019 in “Cell reports” Patient-derived melanocytes can potentially treat vitiligo by restoring skin pigmentation.
1 citations
,
June 2023 in “Journal of steroid biochemistry and molecular biology/The Journal of steroid biochemistry and molecular biology” Vitamin D helps skin stem cells heal wounds by working with a key skin protein.
November 2017 in “Dermatologic Clinics” Men are increasingly interested in cosmetic treatments that enhance masculinity and address aging without downtime, with tailored approaches for different ethnicities and a focus on hair restoration and body contouring.
March 2015 in “Plastic and reconstructive surgery” Human skin has multiple layers and functions, with key roles in protection, temperature control, and appearance.
April 2018 in “Journal of Investigative Dermatology” Arrector pili muscle regulates hair follicle stem cells, DNA methylation needed for hair cycling, and Wnt/B-catenin signaling starts hair growth.
306 citations
,
April 2019 in “International Journal of Molecular Sciences” The skin has a complex immune system that is essential for protection and healing, requiring more research for better wound treatment.
92 citations
,
March 2016 in “Developmental Cell” Zebrafish skin regeneration relies on cell behaviors and reactive oxygen species, with antioxidants reducing and hydrogen peroxide increasing regeneration.
January 2018 in “Stem cell biology and regenerative medicine” The nucleus is key in controlling skin growth and repair by coordinating signals, gene regulators, and epigenetic changes.
June 2008 in “Regenerative Medicine” The book explains the science of tissue repair and regeneration, its medical uses, challenges, and ethical concerns.
85 citations
,
July 2012 in “Cold Spring Harbor perspectives in biology” The skin protects the body and is constantly renewed by stem cells; disruptions can lead to cancer.
49 citations
,
February 2008 in “Stem Cells” Wnt10b helps blood stem cells grow after injury.
44 citations
,
April 2017 in “Genes & development” Scientists found cells in hair that are key for growth and color.
43 citations
,
February 2008 in “Journal of cutaneous pathology” Melanocyte precursors in human fetal skin follow a specific migration pattern and some remain in the skin's deeper layers.
36 citations
,
July 2014 in “Experimental Dermatology” Skin and hair can regenerate after injury due to changes in gene activity, with potential links to how cancer spreads. Future research should focus on how new hair follicles form and the processes that trigger their creation.
31 citations
,
August 2000 in “Journal of Investigative Dermatology” Stem cells are key for hair follicle recovery.
29 citations
,
May 2020 in “npj Regenerative Medicine” Immune cells help regulate hair growth, and better understanding this can improve hair loss treatments.
22 citations
,
July 2012 in “International Journal of Trichology” Miniaturized hairs stay connected to muscle in alopecia areata, allowing possible regrowth, but not in androgenetic alopecia.
19 citations
,
December 2021 in “Stem Cell Research & Therapy” Muse cells from human bone marrow help reduce symptoms of atopic dermatitis in mice.
19 citations
,
March 2017 in “PLoS ONE” PSU are better than THF at regenerating skin layers in lab models.
19 citations
,
April 2016 in “Experimental Dermatology” Melanoblasts migrate to the skin using various pathways, and understanding this process could help with skin disease research.
17 citations
,
January 2013 in “Journal of Cosmetics, Dermatological Sciences and Applications” 3D bioprinting could improve skin repair and treat conditions like vitiligo and alopecia by precisely placing cells.
17 citations
,
May 2011 in “Gene Therapy” Using polyethylenimine-DNA to deliver the hTERT gene can stimulate hair growth and may be useful in treating hair loss, but there could be potential cancer risks.
9 citations
,
April 2019 in “International journal of molecular sciences” Human hair grows better in a special gel that mimics skin.