research Sacituzumab tirumotecan (sac-TMT/MK-2870/SKB264): a novel antibody–drug conjugate in breast cancer
Sacituzumab tirumotecan shows promise in treating breast cancer with manageable side effects.
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research Stem cells, organoids and their applications for human diseases: Special issue of BMB Reports in 2023
Organoids created from stem cells are used to model diseases, test drugs, and develop personalized and regenerative medicine.
research Potential synergistic effects of Haedoksamul-tang and Finasteride of on 5α-reductase inhibition and proliferation of human follicle dermal papilla cells
HST and HST/F promote hair growth and may help treat alopecia.
research Introduction to JID Symposium Proceedings 52nd Annual Montagna Symposium on the Biology of Skin “Stem Cells in Skin” Held at Snowmass, Colorado, USA, June 13–17, 2003
Adult somatic stem cells could be used for future skin therapies.
research DRUG NEWS
The FDA approved a new breast cancer treatment, found flu shots may reduce heart risks, questioned the safety of fast-tracked drug approvals, showed statins don't help with certain pneumonia, and approved a new dementia imaging agent.
research Crown-X: A Novel Menstrual Stem Cell-Based Therapy for Hair Regeneration in Male Pattern Baldness
Crown-X may effectively restore hair in male pattern baldness using menstrual stem cells.
research A phase I study of MK-5108, an oral aurora A kinase inhibitor, in both monotherapy and in combination with docetaxel in patients with advanced solid tumors.
MK-5108 is safe and shows potential against tumors, especially alone.
research Epidermal Stem Cells in Orthopaedic Regenerative Medicine
Epidermal stem cells show promise for treating orthopedic injuries and diseases.
research Streptomyces-derived nano-doxorubicin: Clinical status and patents granted
Nanoparticle delivery can reduce side effects of the cancer drug doxorubicin.
research Stem Cell Therapy in Hair Restoration
Stem cell therapy can help regrow hair.
research Looking Beyond PRP, Exosomes, and Stem Cells
Stem cells, PRP, and exosomes show promise in treating skin conditions but face regulatory and safety challenges.
research Vitamin E TPGS based transferosomes augmented TAT as a promising delivery system for improved transdermal delivery of raloxifene
The new delivery system improved raloxifene's skin absorption and effectiveness against cancer cells.
research Fondation René Touraine
The document concluded that stem cells are crucial for skin repair, regeneration, and may help in developing advanced skin substitutes.
research 2,3,5,4′-Tetrahydroxystilbene-2-O-β-D-glucoside (TSG) from Polygonum multiflorum Thunb.: A Systematic Review on Anti-Aging
TSG from Polygonum multiflorum may help with anti-aging by protecting the brain, heart, bones, and hair.
research Advancing immunotherapy using biomaterials to control tissue, cellular, and molecular level immune signaling in skin
research EGFR : stopping stathmin to start the cycle
EGFR helps hair follicles transition properly by controlling Stathmin levels.
research Tyrosine kinase inhibition and grey hair
Imatinib can repigment grey hair, while SU11428 can cause temporary hair depigmentation.
research Understanding the molecular basis of mesenchymal stem cell stemness: implications for clinical applications
Understanding how mesenchymal stem cells stay undifferentiated can improve their use in treating diseases.
research Clinical Development of Topoisomerase-Interactive Drugs
New drugs targeting DNA enzymes show promise for cancer treatment but have side effects like immune system suppression and hair loss.
research Risk and Benefit of CD133 + Progenitors
CD133+ progenitor cells have therapeutic potential for diabetic ulcers and heart attack recovery, with manageable risks.
research 574 USPlus®Derm reinforces the stem cell niche and prolongs anagen by positively modulating dermal papilla inductivity in occipital male scalp hair follicles
USPlus®Derm may help hair growth and maintain stem cells in male pattern hair loss.
research Strontium: A Potent and Selective Inhibitor of Sensory Irritation and Topical Anti-inflammatory
Strontium can effectively reduce skin irritation and inflammation.
research Research Highlights: Highlights from the latest articles in regenerative medicine
Latest articles show advancements in regenerative medicine.
research Annotated Patent Selections
The document highlights various patents for new compounds with potential treatments for multiple diseases, including cancer, hormonal disorders, and diabetes.
research Formulation of Chitosan-Coated Brigatinib Nanospanlastics: Optimization, Characterization, Stability Assessment and In-Vitro Cytotoxicity Activity against H-1975 Cell Lines
The new Brigatinib nanocarrier is more effective against lung cancer cells than the free drug.
research Methods and Limitations of Augmenting Mesenchymal Stem Cells for Therapeutic Applications
Unmodified mesenchymal stem cells have limited benefits, so ongoing research aims to improve their effectiveness.
research Advances in Stem Cell Therapy: Specific Applications in the Treatment of Cutaneous Radiation Syndrome
Stem cell therapy improves healing and reduces pain in cutaneous radiation syndrome.
research First-in-Man Clinical Trial of the Oral Pan-AKT Inhibitor MK-2206 in Patients With Advanced Solid Tumors
MK-2206 was safe and effectively blocked AKT signaling in cancer patients, warranting more trials.
research FRI378 Estetrol Prolongs Anagen In Healthy Female Scalp Hair Follicles By Positively Modulating Dermal Papilla Functions And Generation Of Progenitor Stem Cells Ex Vivo
Estetrol helps keep scalp hair in the growth phase longer and improves hair follicle health by affecting the hair root and increasing stem cells.
research Guest Editorial: The regenerative dentistry: current approaches and future insights
Regenerative dentistry using stem cells shows promise for healing and rebuilding tissues.