research The long road traveled in hematopoietic stem cell gene therapy
The FDA approved the first gene therapy for a blood disorder after overcoming early challenges and demonstrating patient benefits.
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research Sept4/ ARTS Regulates Stem Cell Apoptosis and Skin Regeneration
Mice without the Sept4/ARTS gene heal wounds better due to more stem cells that don't die easily.
research Septin 4 (SEPT4; ARTS)
Blocking SEPT4 might help heal wounds and regrow hair faster.
research Identification of a secreted BMP antagonist, ectodin, integrating BMP, FGF, and SHH signals from the tooth enamel knot
Ectodin integrates BMP, SHH, and FGF signals in developing ectodermal organs.
research Establishment of an Efficient Primary Culture System for Human Hair Follicle Stem Cells Using the Rho-Associated Protein Kinase Inhibitor Y-27632
A new method using Y-27632 improves the growth and quality of human hair follicle stem cells for tissue engineering and therapy.
research DPSCs and SHED in Tissue Engineering and Regenerative Medicine
DPSCs and SHED have great potential for medical treatments and tissue repair.
research Whole Tooth Regenerative Therapy Using a Bioengineered Tooth Germ
Bioengineered teeth could replace damaged teeth and restore oral functions.
research MSCs, but not mesenchymal stem cells
MSCs should be called "master signaling cells" because they mainly help with cell communication and tissue repair.
research Ion Sequential Therapy Aligned With Pathological Changes Enhances Cardiac Function After Myocardial Infarction
Ion sequential therapy improves heart function after a heart attack.
research A hybrid hydrogel encapsulating human umbilical cord mesenchymal stem cells enhances diabetic wound healing
A new hydrogel with stem cells from the human umbilical cord speeds up healing in diabetic wounds.
research 320 Desmoglein 3-mediated mechanical transadhesion controls epithelial stem cell quiescence
Desmoglein 3 is important for keeping hair follicle stem cells inactive and maintaining their special properties.
research Therapeutic effects of human amniotic mesenchymal stem cell-derived exosomes on stem cell proliferation in irradiated salivary glands via the Wnt pathway
Exosomes from stem cells help repair irradiated salivary glands by boosting cell growth.
research Advancing skin model development: A focus on a self-assembled, induced pluripotent stem cell-derived, xeno-free approach
A new ethical skin model using stem cells offers a reliable alternative for dermatological research.
research Strontium zinc silicate simultaneously alleviates osteoporosis and sarcopenia in tail-suspended rats via Piezo1-mediated Ca2+ signaling
Strontium zinc silicate may help treat osteoporosis and muscle loss.
research Shaping epithelial tissues by stem cell mechanics in development and cancer
research Modulation of hair growth by topical drug delivery enhanced by STAR particles
STAR particles can improve the effectiveness of topical hair growth treatments without causing skin irritation.
research Distinct stem cells contribute to mammary gland development and maintenance
Different types of long-lasting stem cells are responsible for the growth and upkeep of the mammary gland.
research Differentiation of Human Dermal Mesenchymal Stem Cells into Cardiomyocytes by Treatment with 5-Azacytidine: Concept for Regenerative Therapy in Myocardial Infarction
Skin stem cells were turned into heart cells using a chemical, suggesting a new way to treat heart attacks.
research ZmSPL10, ZmSPL14 and ZmSPL26 act together to promote stigmatic papilla formation in maize through regulating auxin signaling and ZmWOX3A expression
ZmSPL10, ZmSPL14, and ZmSPL26 genes are essential for forming maize structures needed for pollen capture and kernel production.
research Long-term renewal of hair follicles from clonogenic multipotent stem cells
Adult stem cells from rat whisker follicles can regenerate hair follicles and sebaceous glands.
research Tcf3 and Lef1 regulate lineage differentiation of multipotent stem cells in skin
Tcf3 and Lef1 are key in deciding skin stem cell roles.
research Engineered exosomes and composite biomaterials for tissue regeneration
Exosomes show promise for future tissue regeneration.
research Over-expression of thymosin beta4 promotes abnormal tooth development and stimulation of hair growth
Too much thymosin beta4 causes weird teeth and more hair growth in mice.
research Corneal epithelial‐like transdifferentiation of hair follicle stem cells is mediated by pax6 and β‐catenin/Lef‐1
Hair follicle stem cells can become corneal-like cells with the help of pax6.
research Tribuloside acts on the PDE/cAMP/PKA pathway to enhance melanogenesis, melanocyte dendricity and melanosome transport
Tribuloside can increase skin pigmentation by enhancing melanin production and distribution.
research Targeted cell delivery of mesenchymal stem cell therapy for cardiovascular disease applications: a review of preclinical advancements
New methods improve stem cell delivery for heart disease, but challenges remain.
research Characterizing the cellular diversity and molecular signatures within the hair follicle dermal stem cell lineage
Unique genes in hair follicle cells help tissue regeneration.
research Transcriptional profiling of putative human epithelial stem cells
Alpha 6 + /MHCI - cells have stem cell traits and are similar to mouse hair follicle stem cells.
research Characterization of Growth Secondary Hair in Min Pig Activated by Follicle Stem Cell Stimulated by Wnt and BMP Signaling Pathway
Wnt and BMP pathways stimulate hair growth in Min pigs, with Wnt being more effective.
research Stem and cancer cells Wnt long telomeres
A pathway helps maintain long telomeres in both stem and cancer cells.