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BI 2536 had limited effectiveness against several advanced cancers and caused significant side effects.

The document introduced a new naming system for keratin-associated proteins to improve clarity and communication across species.

High LGR5 levels in glioblastoma indicate poor prognosis and are essential for cancer stem cell survival.

Fetal skin cells from a cell bank heal wounds faster and with less scarring than adult cells.

Organoids and organ chips can improve eye disease research and treatment.

Keratin films from human hair can potentially replace human nail plates for drug testing.

Prolactin affects the production of different keratins in human hair, which could lead to new treatments for skin and hair disorders.

Sexual activity can spread T. interdigitale, needing quick antifungal treatment to avoid permanent scarring.

Spermidine may help reduce hair loss and deserves further testing as a treatment.

αMSH may help regulate immune responses in hair follicles and its disruption could lead to hair loss.

Mutations in the LSS gene cause a rare type of hereditary hair loss.

Hormones control keratin production in skin and hair.

LY191704 is a compound that effectively blocks a specific enzyme involved in hormone conversion and could help treat enlarged prostate and hair loss.

DHEA treatment helps grow pubic hair and boosts mood in girls with adrenal issues.

JunB is crucial for maintaining healthy skin and hair follicles.

DMBT1 and galectin-3 may help suppress epithelial skin cancer.

Cytokines and neuropeptides are key in controlling androgen levels, affecting skin and hair conditions.

Particles similar in size to hair cells penetrate hair follicles better.

A nonviral method was developed to label and culture human hair follicle stem cells.

Thyroid hormones affect hair follicle stem cells by promoting differentiation and reducing growth.

A specific genetic mutation may increase male pattern baldness risk, especially in Europeans.

Hormones and neuroendocrine factors control hair growth and color, and more research could lead to new hair treatment options.

Cortisone reductase deficiency can cause high androgen and cortisol levels and may be missed in women with similar symptoms.

CRAC channels are crucial for the development and function of specialized immune cells, preventing severe inflammation and autoimmune diseases.

Claudin-1 is important for the barrier function and growth of hair.

GLI2 increases follistatin production in human skin cells.

AR/EDA2R gene linked to early-onset female hair loss, but 20p11 gene not involved.

The outer layer of Merino wool is rich in sulfur proteins, making it resistant to damage.

Understanding cellular interactions in VCA may lead to better treatments and reduce rejection.