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Researchers developed a method to measure different forms of a drug that could help treat prostate issues and hair loss, and found how these forms behave in animals.

Ketoconazole increases finasteride's effectiveness and lifespan in the body.

Finasteride and dutasteride's effects are mainly due to target binding saturation and slow enzyme turnover.

The hair follicle pathway significantly affects how easily water-loving chemicals pass through the skin.

Different factors affect where drugs are absorbed in the small intestine, which is important for effective medication use.

Human enzymes can detoxify harmful substances but might also increase their cancer risk.

Finasteride affects UGT1A4 enzyme, but not enough to cause issues when combined with other drugs.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

Formyl-peptide receptor agonists could be new anti-inflammatory drugs.

Nanozymes greatly improve biocatalysis by being stable, efficient, and versatile.

A new method creates unique chemical structures that could improve drug discovery.

PHAs are promising biodegradable materials for medical and dental uses.

Females have higher Dechlorane Plus in hair, while males have more in dorm dust.

A new, efficient method was developed to synthesize a specific compound and its derivatives.

Mutants of CYP154C2 enzyme significantly improved steroid conversion efficiency.

The study created a model to help design new inhibitors for steroidal 5α-reductase enzymes.

Finasteride effectively inhibits the enzyme steroid 5 alpha-reductase II.

Using β-cyclodextrin derivatives improves the solubility and bioavailability of steroidal drugs.

CYP154C7 enzyme can effectively modify steroids and is promising for commercial use.

A new, efficient method creates sulfinimidate esters from sulfenamides and alcohols without metals.

A new method using solid-state circular dichroism anisotropy can distinguish similar chiral compounds better than traditional techniques.

The method produces finasteride with a 92% yield.

A new method efficiently creates biaryl N-oxides with potential for cancer treatment and drug development.

Benzo[c]quinolizin-3-ones are effective nonsteroidal inhibitors of human steroid 5α-reductase 1.

Optimizing the structure of a specific compound greatly improved its effectiveness and precision for treating diabetic complications.

Key enzymes control androgen levels, affecting hormone activity and potential treatments.

The research found that the properties of solid-state Electronic Circular Dichroism (ss-ECD) are influenced by the orientation of local crystals, which could help in examining and mapping chiral materials like pharmaceutical ingredients.