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Scientists made new substances that can block an enzyme linked to prostate issues and hair loss, with potential for creating a new treatment.

Finasteride treats enlarged prostate and hair loss, but may cause side effects in some patients.

Plant-based compounds may offer safer prostate cancer treatment with fewer side effects.

Finasteride, a drug, can block the seizure-preventing effects of a hormone called progesterone in mice.

The development of breeding tubercles in male zebrafish relies on a specific enzyme that processes hormones.

New steroid compounds effectively inhibit 5α-reductase and may treat hair loss.

Men with male-pattern baldness have higher levels of certain testosterone metabolites and may have more active androgen metabolism.

We need to learn more about 5α-reductases and neuroactive steroids to safely make drugs targeting these enzymes.

Enzymes called 5α-reductases have many body functions and need more research to safely use inhibitors.

New pregnane derivatives were more effective than finasteride at inhibiting a key enzyme for male pattern baldness.

The skin's ability to produce hormones is linked to various skin conditions, and better understanding this process could lead to new treatments.

Compounds 15, 20, and 25 are strong inhibitors of human steroid 5α-reductase type 2.

Hormonal treatments can help with acne, especially in women, by lowering androgen levels or blocking their effects.

Vitamin E affects liver metabolism, enhancing stress resistance, reducing blood clotting, and altering hormone processing.

4-(4-Phenoxybenzoyl)benzoic acid derivatives can both increase and decrease certain types of reactive oxygen species, and may be relevant to hair loss.

Testosterone helps human pancreatic cells increase insulin release.

Testosterone and dihydrotestosterone play a role in women's health issues like excess hair and baldness, and treatments blocking these hormones may help.

The enzyme 5α-reductase is key in causing psychotic-like effects from sleep deprivation.

Phytochemicals may offer safer alternatives to synthetic drugs for prostate cancer treatment.

Plant-based compounds might be effective, low-side-effect treatments for prostate cancer by blocking a specific enzyme.

Asparagus racemosus root extract reduced sebum and pore size in men but not in women.

Rice husk and bran extracts from the Bue Bang 3 CMU variety can potentially treat hair loss due to their antioxidant, anti-inflammatory, and anti-androgenic properties.

MK-0773 is a moderate inhibitor of the SRD5A2 enzyme.

Blocking the enzyme 5α-reductase can shrink the prostate and help treat enlarged prostate issues.

The triterpenoids from Ganoderma lucidum can block testosterone effects and may help treat enlarged prostate.

The study created a model to help design new inhibitors for steroidal 5α-reductase enzymes.

New chemical compounds were made that effectively block an enzyme linked to prostate growth.

Certain 4-azasteroids are effective at blocking the enzyme that processes testosterone in human skin and could help treat acne, excessive hair growth, and male pattern baldness.

Researchers developed a new method to find substances in herbs that can block a specific enzyme linked to hair loss.

11α-Hydroxyprogesterone is changed into different substances by certain enzymes and may play a role in prostate cancer.