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Changing neuroactive steroids in baby male rats affects their memory and learning differently as they grow up.

5α-reductase inhibitors can cause sexual problems, higher risk of aggressive prostate cancer, and depression.

Women with hyperandrogenism have higher androgen levels and lower SHBG, which may contribute to conditions like excessive hair growth and early puberty.

Androgenic steroids can slow down or stop the growth of certain skin fungi.

Low testosterone does not prevent prostate cancer in men with type 1 diabetes.

Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.

Testosterone and dihydrotestosterone play a role in women's health issues like excess hair and baldness, and treatments blocking these hormones may help.

Advancements in male reproductive medicine are ongoing, but more research and improved treatments are needed in several areas.

Hormonal treatments can help with acne, especially in women, by lowering androgen levels or blocking their effects.

Finasteride treats baldness but may cause lasting sexual side effects.

The new progesterone derivatives effectively inhibit 5α-reductase and bind to the androgen receptor.

Cuscuta reflexa extracts and an isolate promoted hair growth and could be natural treatments for hair loss.

Androgenetic alopecia involves genetics, hormones, and can be treated with medications or surgery.

Dihydrotestosterone (DHT) is crucial for conditions like male-pattern baldness and acne, and measuring a byproduct, androstanediol glucuronide, is a better way to assess DHT's effects than DHT blood levels.

Male hormones and their receptors play a key role in hair loss and skin health, with potential new treatments being explored.

Many treatments for hair loss lack proper testing and FDA approval, so their effectiveness is uncertain.

Steroid 5α-reductase evolved from protists and diversified in eukaryotes, with specific roles in mammals and plants.

Finasteride blocks progesterone production in specific tumor cells, potentially causing side effects.

Molecular diagnostics help identify genetic defects causing endocrine diseases, improving diagnosis and treatment options.

The mouse model suggests male pattern baldness may be due to an enzyme increasing DHT and higher androgen receptor levels in hair follicles.

Women with PCOS have higher 5alpha-reductase activity, affecting steroid levels.

Women with PCOS have higher 5alpha-reductase activity, affecting steroid levels.

New pregnane derivatives were more effective than finasteride at inhibiting a key enzyme for male pattern baldness.

A 13-year-old with 46 XY DSD had ambiguous genitalia due to incomplete masculinization.

Serenoa repens and N-acetyl glucosamine/milk proteins complex may help with hair growth and prevent hair loss.

Finasteride effectively treats BPH but may increase sexual dysfunction risk.

New hormonal treatments for enlarged prostate show promise for safer, effective non-surgical options.

Finasteride reduces hair growth in women with hirsutism and works better with electrolysis.

Finasteride and dutasteride may cause metabolic issues like liver disease and diabetes.

Some hair loss can be treated, especially in women due to nutrition, but some types remain untreatable.