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A patient with a nerve disorder died from infection complications after developing insulin resistance from a treatment.

Finasteride's effect on hair loss and prostate enlargement depends on its binding to an enzyme, with maximum impact at 0.2 mg dose.

Blocking a specific enzyme might help treat obesity and diabetes, but more research is needed to ensure it's safe.

Too much AKR1C3 enzyme causes resistance to finasteride by increasing testosterone.

Certain mutations in the H6PD gene cause Cortisone Reductase Deficiency by affecting hormone production.

The study found that urine metabolites M1b or M4 are the best indicators of ATD use in horses, with detection possible up to 77 hours in urine and 28 hours in blood.

Two non-steroidal antiandrogens, RU 58841 and RU 56187, form a common metabolite at different rates, which may influence their effects; RU 56187 could be used for prostate cancer treatment and RU 58841 for acne treatment.

Finasteride doesn't affect erections much, but may decrease libido in men.

Progesterone byproduct 5αP stimulates mammary tumor growth, but finasteride can suppress it.

Certain inhibitors can potentially treat prostate cancer and other hormone-dependent conditions by controlling sex hormone levels in cells.

Hirsute women have lower type 2 17β-HSD enzyme levels, which improve with treatment.

Beard hair follicles convert testosterone to 5α-dihydrotestosterone most intensively.

The safety and effectiveness of gender-affirming treatments for children are uncertain, with potential long-term risks like infertility.

Hair analysis shows low progesterone in anorexia patients, unchanged by short-term weight gain.

Finasteride helps treat prostate issues and may prevent prostate cancer in high-risk men.

Metformin improved menstrual cycle regularity and signs of hyperandrogenism in adolescent girls with type 1 diabetes but did not improve blood sugar control.

Reduced AR gene methylation may cause early pubic hair growth in girls.

Intravaginal testosterone cream improves sexual satisfaction and reduces vaginal discomfort in postmenopausal women on breast cancer treatment without affecting hormone levels.

Reducing phthalate exposure may help prevent early puberty in girls.

Anabolic steroid users may face higher risk of severe COVID-19.

Androgens, like DHT, affect hair growth and treatments like finasteride may help.

Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.

Epristeride's metabolism in zebrafish helps improve doping detection methods.

Steroid-producing capabilities in certain cancers may contribute to treatment resistance.

The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.

S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.

New steroidal compounds could be effective for treating conditions related to 5α-reductase enzyme activity.

The study created a new method to test drugs that affect hormone processing in skin.

Finasteride irreversibly affects human steroid 5α-reductase 2, providing insight into its catalytic mechanism and disease-related mutations.

Finasteride poorly inhibits type 1 5AR, affecting its effectiveness.