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New targets for making and using brain-synthesized steroids could lead to better treatments for brain disorders and alcoholism.

Key enzymes control androgen levels, affecting hormone activity and potential treatments.

New compounds were made that block an enzyme linked to breast cancer better than existing treatments.

Neuroactive steroids could become safe, effective treatments with more understanding of their complex brain actions and metabolism.

Gut bacteria affect steroid levels, influencing health conditions and potential treatments.

Severe COVID-19 may increase lung cancer risk and affect treatment in women due to hormonal changes.

Rare ovarian tumors can cause increased male hormones in postmenopausal women; surgery is an effective treatment.

A woman got a skin condition from misusing a steroid cream, which improved after she stopped using it and started a new treatment.

The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.

Certain steroids in the brain affect mood and symptoms of depression, and treatments targeting these steroids show promise for improving these symptoms.

Steroid Sulfatase inhibitors show promise in treating hormone-dependent disorders like cancers, hair loss, and acne, with 667COUMATE being a potential candidate for breast cancer treatment trials.

Certain compounds, especially those with a propionic substituent, could potentially be new treatments for hair loss and similar disorders.

A boy with a rare skin condition and kidney disease improved with cyclosporine after steroids failed, suggesting a new treatment approach.

Certain natural compounds can block an enzyme linked to prostate enlargement and hair loss, showing potential for new treatments.

A new method was created to test the effectiveness of Dihydrotestosterone (DHT) inhibitors, like finasteride and dutasteride, in human and fish cells. The results showed fish cells are more sensitive to these treatments, and dutasteride works better than finasteride in all tested cells.

The research identified and described a gene important for hormone conversion in endangered catfish, which varies in activity during different reproductive stages and after hormone treatment.

Tofacitinib was effective for severe, treatment-resistant hair loss without side effects.

A young woman had a rare, aggressive ovarian tumor that was hard to diagnose and treat, leading to disease progression despite treatment.

A rare ovarian tumor was diagnosed in a woman from North Brazil, and surgery is the preferred treatment.

Ovarian steroid cell tumors should be considered in adults with hirsutism and high testosterone, with surgery as the main treatment.

Optical coherent tomography can effectively detect steroid use by analyzing hair changes.

A rare scalp condition mainly in older women can be treated with various alternatives to steroids, which may have fewer side effects.

LY320236 is a strong blocker of two enzymes that change testosterone into dihydrotestosterone and might help treat conditions related to male hormones.

The combination of vitamin D analogues with potent steroids is a favorable treatment for alopecia areata with fewer side effects.

Different animals have unique versions of the enzyme that changes testosterone into another hormone, which is important for creating effective treatments for prostate and hair loss conditions.

Women with non-classical congenital adrenal hyperplasia have higher levels of certain steroids, which can be reduced by treatment.

A dog developed skin issues from too many steroids, but reducing steroids and using a specific treatment fixed the problems.

The research found that compound 6, a newly created steroid, is more effective at inhibiting 5α-reductase (an enzyme) than current treatments, suggesting it could be a better option for treating urinary tract symptoms in men.

Effective treatment for hidradenitis suppurativa varies, with antibiotics commonly used and surgery as an option, but no single method is universally successful.

Some treatments like intralesional steroids and 5α-reductase inhibitors are effective for frontal fibrosing alopecia, but more research is needed.