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Certain ESR1 gene variations may affect hormone levels and fat distribution in women with high male hormone levels.

Finasteride changes antioxidant enzyme expression, possibly affecting sperm protection in rats.

Dihydrotestosterone specifically binds to hamster sebaceous glands, with a higher affinity than testosterone.

Idiopathic hirsutism may be linked to increased enzyme activity.

Androgens can affect glucocorticoid signaling in specific mouse brain areas.

Women with female pattern hair loss have higher levels of certain androgens, suggesting increased androgen exposure to hair follicles.

17β-estradiol lowers polyamine oxidase levels in breast cancer cells through estrogen receptor 2.

Researchers found new potential but less potent rat enzyme inhibitors using a 3D model.

The document concludes that the androgen receptor's structure and function are complex, affecting how it regulates genes and is involved in diseases like prostate cancer.

Androgenic steroids can slow down or stop the growth of certain skin fungi.

A rare ovarian tumor caused high male hormone levels, but surgery fixed it.

Steroid sex hormones activate matriptase in prostate cancer cells but not in breast cancer cells.

Ovarian and stress hormones can change GABA A receptors through neurosteroids.

Compound 7b is a promising candidate for treating benign prostatic hyperplasia and prostate cancer.

Canine hair follicle cells metabolize DHEA and testosterone differently than human cells.

The chemicals 17βC and its methyl ester can block the effects of testosterone on hamster skin but not the effects of DHT.

Neurosteroids may help treat disorders with too much dopamine activity.

Human hair can be used to measure reproductive hormones.

Selective non-steroidal inhibitors of 5α-reductase type 1 can help treat DHT-related disorders.

Testosterone boosts red blood cell production and changes iron metabolism without needing dihydrotestosterone.

SRD5A2 enzyme expression varies in benign prostates and can be influenced by inflammation, affecting treatment options.

Different halogens on progesterone derivatives can either block or mimic male hormone effects, depending on their type and amount.

Females with 5 alpha-reductase-2 deficiency have less body hair, no acne, normal fertility, and delayed menarche.

Adding a specific gene to skin cells can help treat skin disorders like psoriasis.

Male rats have androgen receptors in their liver, which are different from proteins that bind estrogen.

The method can measure multiple steroids in human hair to study long-term steroid metabolism, especially in newborns and children.

CYP2B12 enzyme in skin cells converts arachidonic acid into specific bioactive lipids.

Thai rice bran extracts, especially from Tubtim Chumphae rice, can significantly reduce the activity of hair loss genes, with x-tocopherol showing potential as an anti-hair loss product.

5α-reduced neurosteroids may help regulate glial cell differentiation.

Testosterone treatment may change estrogen receptor methylation in AFAB individuals.