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Retinoic acid, glucocorticoids, and IGF1 increase IGFBP-3 production in human dermal papilla cells, affecting hair growth.

FP-1 is a key protein in rat hair growth, active only during the growth phase.

Increased HSD11B1 enzyme expression is linked to higher body fat and insulin resistance.

Researchers found a gene in hamsters that responds to male hormones and may be indirectly controlled by them.

Testosterone, progesterone, and levonorgestrel change enzyme levels related to fat production in hamster skin, which could affect skin oil and acne.

PDGF signaling is crucial for maintaining fat stem cells in the skin, and its level of activation can either preserve these cells or cause fibrosis.

Blocking a specific enzyme can reduce the negative impact of stress hormones on hair growth cells.

Blocking 11β-HSD1 reduces stress hormone damage in hair growth cells.

SCF and ET-1 together significantly increase skin pigmentation and melanin production.

Androgen is important in controlling stem cell differentiation, reducing fat development, and increasing lean mass.

17β-estradiol boosts APE1/Ref-1 secretion in cells and mice via a calcium-dependent pathway.

Steroidogenesis inhibitors change but don't stop androgen production in prostate cancer.

Increased 11β-HSD1 activity in skin may contribute to aging and could be targeted to reduce aging effects.

Reducing 5α-reductase activity helps endometrial cells differentiate, aiding pregnancy.

Blocking CRF1 receptors improved male hormone levels and reduced testicular tumor size in men with a specific adrenal condition.

Finasteride irreversibly affects human steroid 5α-reductase 2, providing insight into its catalytic mechanism and disease-related mutations.

A specific metabolite, not a receptor protein, triggers the production of certain kidney enzymes, but this process is disrupted in mice with a mutation causing testicular feminization.

TRF1 is crucial for creating and maintaining stem cells and marks both pluripotent and adult stem cells.

Finasteride effectively inhibits the enzyme steroid 5 alpha-reductase II.

Prostate cells have proteins that bind to specific hormones, which can increase protein production when activated by these hormones.

Four-amino acid part makes enzyme sensitive to finasteride.

High testosterone levels can harm fertility by disrupting the LIF signaling pathway in the uterus.

Human prostate cells produce more WISP1/CCN4 when there's not enough oxygen.

Foxp1 helps control hair stem cell growth and response to stress during hair growth cycles.

Steroid sulfatase inhibitors could help treat hormone-related disorders and cancers.

The FOXN1 gene is crucial for developing immune cells and preventing immune disorders.

Megestrol acetate helps fat-derived stem cells grow, move, and turn into fat cells through a specific receptor.