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Testosterone is important for male sexual traits, reproduction, muscle and bone health, blood production, and metabolism, and works both directly and after being changed into other hormones.

Differences in enzyme activity and androgen receptors in hair follicles may explain why hair loss appears differently in men and women.

A new compound with strong antiandrogenic effects was found, potentially useful for treating conditions like acne and prostate cancer.

Mutations in the glucocorticoid receptor gene cause reduced sensitivity to glucocorticoids and may lead to poor response to treatment.

STK11 gene variations do not predict how well metformin will work for PCOS, but may affect hair loss and excess hair growth.

Sex hormones affect brain cells differently in males and females.

The AMHR2-482A>G gene change is linked to higher PCOS risk.

Finasteride boosts immune cells that suppress T-cells, possibly helping with immune disorders but may increase cancer risk.

TPA strongly increases ODC activity in certain skin cells, potentially aiding tumor growth.

Different types of PCOS in Chinese Han women show varying levels of male hormone and metabolic issues.

A boy with a new NR5A1 gene mutation has a sex development disorder without affecting his adrenal glands.

RXR and RAR proteins in skin may help with cell growth, hair growth, and gland function.

The new progesterone derivatives effectively inhibit 5α-reductase and bind to the androgen receptor.

Natural herbal compounds might treat certain medical conditions by reducing DHT levels, but more research is needed to confirm their effectiveness and safety.

A boy with a rare skin condition and kidney disease improved with cyclosporine after steroids failed, suggesting a new treatment approach.

Introducing the rat OTC gene partially corrected OTC deficiency in mice.

Certain natural compounds can block an enzyme linked to prostate enlargement and hair loss, showing potential for new treatments.

Reducing granulosa cell pyroptosis may improve oocyte maturation in PCOS.

Estrogen Receptor ß (ERß) is the main hormone controller in human skin and hair follicles, not Estrogen Receptor α (ERα) or the Androgen Receptor (AR).

New compounds show promise as nonsteroidal treatments for hair loss.

Breathing in newborn rats is affected differently by hormones based on their sex.

Accurate protein modeling can help develop new treatments for prostate cancer and other diseases.

Androgen receptor activity is influenced by hormones, co-factors, modifications, and mutations.

PCOS and related metabolic issues often run in families.

The SOSTDC1 gene is crucial for determining sheep wool type.

Certain gene variations are found in people with polycystic ovary syndrome.

A new compound effectively inhibits human 5α-reductase 1.

Monitoring steroid hormones in blood can better detect testosterone doping.

Androgens and estrogens are crucial for insulin secretion in males.