research Study of gene expression alteration in male androgenetic alopecia: evidence of predominant molecular signalling pathways
Hair loss involves immune responses, inflammation, and disrupted signaling pathways.
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research Advances in male hormone substitution therapy
New treatments for low male hormones improved sexual function and mood but had unclear risks, especially for older men.
research Acne: Hormonal concepts and therapy
Hormones, especially androgens, play a big role in acne, but most acne sufferers don't have a hormone disorder. Hormonal treatments, including birth control pills, can be very effective for women whose acne doesn't improve with regular treatments.
research 5α-Reduced glucocorticoids: a story of natural selection
Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.
research Consequences of steroid-5α-reductase deficiency and inhibition in vertebrates
Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.
research Resveratrol derivatives: a patent review (2009 – 2012)
New resveratrol-related compounds show promise for treating various health issues but need more research for clinical use.
research Hair Disorders
Understanding normal hair growth and loss in children is key to diagnosing and treating hair disorders.
research The effects of narrowbands of visible light upon some skin disorders: a review
Visible light can improve skin disorders and hair loss, but more research is needed to understand long-term effects.
research Modelling androgen synthesis and action during human sexual differentiation
Male sexual differentiation is regulated independently, while female differentiation occurs in an androgenic environment, affecting conditions like congenital adrenal hyperplasia.
research Steroid Sulfatase: Molecular Biology, Regulation, and Inhibition
The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.
research What should it take to describe a substance or product as 'sperm-safe'
Products should be called 'sperm-safe' only after thorough, well-designed tests.
research Sexual Hormones in Human Skin
Human skin makes sexual hormones that affect hair growth, skin health, and healing; too much can cause acne and hair loss, while treatments can manage these conditions.
research Patched-assoziierte Tumoren: Modifikatorgene und Pathogenese
The document concludes that the development of certain tumors is influenced by genetic background and that a specific gene modification can lead to tumor regression and reduced growth.
research Targets to treat androgen excess in polycystic ovary syndrome
The conclusion is that while oral contraceptive pills are effective for PCOS-related high androgen levels, new treatments with fewer side effects are needed.
research Three-Dimensional Proteome-Wide Scale Screening for the 5-Alpha Reductase Inhibitor Finasteride: Identification of a Novel Off-Target
Finasteride may affect PNMT, causing side effects.
research Vitamin D, Lipid Metabolism and Prostate Cancer
Vitamin D may help regulate cholesterol and influence prostate cancer development.
research Overexpression of HE4/WFDC2 gene in mice leads to keratitis and corneal opacity
Overexpression of the HE4 gene in mice causes eye inflammation and cloudiness.
research Hormones and the pilosebaceous unit
Hormones significantly affect hair and oil gland function in the skin, and more research is needed on skin-related hormone disorders.
research Pharmacology of Induced Artificial Platelets in Regenerative Medicine: Beyond Transfusion
iPSC-derived artificial platelets show promise for consistent and effective regenerative therapies.
research Androgens modulate endometrial function
Androgens affect the function and health of the endometrium.
research Chrousos syndrome: from molecular pathogenesis to therapeutic management
The review suggests thorough evaluation and genetic testing for proper diagnosis and treatment of Chrousos syndrome.
research Nutrition Strategy and Life Style in Polycystic Ovary Syndrome—Narrative Review
Eating healthy, exercising, and taking certain supplements can help manage Polycystic Ovary Syndrome symptoms.
research Potential role and therapeutic interests of myo-inositol in metabolic diseases
Myo-inositol supplements may improve insulin sensitivity and help with conditions like PCOS and gestational diabetes, but more research is needed.
research Prostate-Specific Antigen as a Marker of Hyperandrogenism in Women and Its Implications for Antidoping
PSA levels could help detect illegal steroid use in female athletes but face challenges like cost and PCOS prevalence.
research Nutrition of women with hair loss problem during the period of menopause
Eating a balanced diet with specific nutrients is important for menopausal women to manage hair loss.
research Topical and transdermal lipid-polymer hybrid nanoparticles (LPN): an integration in advancing dermatological treatments
Lipid-polymer hybrid nanoparticles show promise for skin treatments but need better formulation strategies.
research Hair Regenerative Mechanisms of Red Ginseng Oil and Its Major Components in the Testosterone-Induced Delay of Anagen Entry in C57BL/6 Mice
Red ginseng oil and its components help promote hair regrowth and could treat hair loss.
research Phytochemicals in the Management of Polycystic Ovary Syndrome, Endometriosis, and Menstrual Irregularities
Plant compounds may help manage PCOS, endometriosis, and menstrual issues.
research Carthami flos: a review of its ethnopharmacology, pharmacology and clinical applications
Safflower has been used in traditional medicine for centuries and shows promise in treating heart, brain, and inflammatory conditions, but more research is needed to ensure its safety.
research The Postnatal Offspring of Finasteride-Treated Male Rats Shows Hyperglycaemia, Elevated Hepatic Glycogen Storage and Altered GLUT2, IR, and AR Expression in the Liver
Finasteride-treated male rats' offspring had altered glucose metabolism, potentially increasing diabetes risk.